Stephens C J
St. John's Dermatology Centre, St. Thomas' Hospital, London, U.K.
Clin Exp Rheumatol. 1992 Sep-Oct;10(5):489-92.
Sneddon's syndrome refers to the rare association of extensive livedo reticularis with multiple ischaemic cerebrovascular episodes. Endarteritis obliterans is the most common cutaneous pathology. It is likely that several pathogenic mechanisms may give rise to Sneddon's syndrome, as the condition is associated with a high incidence of generalised atherosclerosis, hypertension, valvular heart disease and the presence of antiphospholipid antibodies.
斯内登综合征指广泛的网状青斑与多发性缺血性脑血管事件的罕见关联。闭塞性动脉内膜炎是最常见的皮肤病理表现。由于该病症与全身性动脉粥样硬化、高血压、心脏瓣膜病以及抗磷脂抗体的存在发生率较高相关,所以可能有多种致病机制导致斯内登综合征。