Buijsse B, Feskens E J M, Kromhout D
Rijksinstituut voor Volksgezondheid en Milieu (RIVM), Centrum voor Voeding en Gezondheid, Postbus 1, 3720 BA Bilthoven.
Ned Tijdschr Geneeskd. 2003 Oct 11;147(41):2007-11.
Vitamin E is a fat-soluble antioxidant and is possibly involved in the prevention of coronary heart disease by inhibiting oxidative modification of LDL cholesterol. The results of studies on the association between vitamin-E intake and coronary heart disease are inconsistent in observational studies and absent in large-scale intervention studies. This may be the consequence of confounding in observational studies and imperfections in the design of intervention trials. Another explanation is that vitamin E may only function protectively in the presence of sufficient co-antioxidants. At present, there is no evidence that vitamin E lowers the risk of coronary heart disease.
