Ilić Miroslav P, Dzolev Asen, Kiralj Aleksandar
Klinika za maksilofacijalnu hirurgiju, Institut za hirurgiju, Klinicki centar, Novi Sad.
Med Pregl. 2003 Jul-Aug;56(7-8):322-5. doi: 10.2298/mpns0308322i.
Lower lip squamous cell carcinoma is the most common oral carcinoma. In relation to other oral carcinomas, it has a better clinical course. If regional metastases appear, lower lip carcinoma has a very poor prognosis.
This study included patients treated for lower lip squamous cell carcinoma in the period 1984-2001. We examined neck metastases and time of their appearance after operation of the primary neoplasm.
Our retrospective study included 305 patients with lower lip carcinoma in a twelve-year period. Out of this number, 293 had no positive neck lymph nodes, and only 12 patients had (4%). More than 75% of metastases appeared in the first year after surgery of the primary neoplasm. Contra-lateral metastases were most common.
Taking into consideration the percentage of metastases, particularly during the first year after surgery, we suggest identification of sentinel lymph nodes and depending on PH finding one should decide about the type of neck operation. Frequent check-ups are necessary, especially during the first year.
下唇鳞状细胞癌是最常见的口腔癌。与其他口腔癌相比，其临床病程较好。若出现区域转移，下唇癌的预后极差。
本研究纳入了1984年至2001年期间接受下唇鳞状细胞癌治疗的患者。我们检查了颈部转移情况以及它们在原发性肿瘤手术后出现的时间。
我们的回顾性研究在12年期间纳入了305例下唇癌患者。其中，293例颈部淋巴结无阳性表现，仅有12例患者出现阳性（4%）。超过75%的转移发生在原发性肿瘤手术后的第一年。对侧转移最为常见。
考虑到转移的百分比，尤其是在手术后的第一年，我们建议识别前哨淋巴结，并根据病理结果决定颈部手术的类型。定期检查是必要的，尤其是在第一年。
