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喉切除术后咽皮肤瘘的预防:纪念大学的经验

Prevention of postlaryngectomy pharyngocutaneous fistula: the Memorial University experience.

作者信息

Smith Thomas J, Burrage Kenneth J, Ganguly Pradip, Kirby Simon, Drover Christopher

机构信息

Department of Otolaryngology, St. Clare's Mercy Hospital Foundation, St. John's, Newfoundland.

出版信息

J Otolaryngol. 2003 Aug;32(4):222-5. doi: 10.2310/7070.2003.41697.

Abstract

OBJECTIVES

The purpose of this study was to compare the efficacy of a pectoralis major myogenous flap in the prevention of pharyngocutaneous fistula in patients who have undergone total laryngectomy. Our secondary objective was to estimate the economic saving to our health care system.

DESIGN

Retrospective clinical study.

SETTING

Grace General Hospital, St. Clare's Mercy Hospital, H. Bliss Murphy Cancer and Research Centre, St. John's, Newfoundland.

MATERIALS AND METHODS

Two hundred and twenty-three consecutive total laryngectomy procedures performed between June 1978 and December 2001 were reviewed. The fistula rate in laryngectomy patients prior to 1988 without pectoralis major myogenous flaps (group A) was compared with that of patients after June 1988 who had this flap routinely used at primary surgery (group B). Analysis of risk factors within those two groups was essentially similar.

RESULTS

In group A, the overall pharyngocutaneous fistula rate was 22.9%. The fistula rate in group B was less than 1%.

CONCLUSION

Our study has demonstrated that at our tertiary care head and neck oncology centre, we have dramatically decreased the incidence of postlaryngectomy pharyngocutaneous fistula. By the routine addition of a pectoralis major myogenous flap to cover the pharyngeal defect at surgery, we have substantially and dramatically reduced patient morbidity and mortality and reduced hospital stay, with major financial savings to the health care system.

摘要

目的

本研究旨在比较胸大肌肌源性皮瓣在预防全喉切除术后患者咽瘘方面的疗效。我们的次要目的是评估对我们医疗保健系统的经济节省情况。

设计

回顾性临床研究。

地点

加拿大纽芬兰圣约翰市的格雷斯综合医院、圣克莱尔慈善医院、H. 布利斯·墨菲癌症与研究中心。

材料与方法

回顾了1978年6月至2001年12月期间连续进行的223例全喉切除术。将1988年以前未使用胸大肌肌源性皮瓣的喉切除患者(A组)的瘘管发生率与1988年6月以后在初次手术中常规使用该皮瓣的患者(B组)的瘘管发生率进行比较。两组内危险因素的分析基本相似。

结果

A组总的咽瘘发生率为22.9%。B组的瘘管发生率低于1%。

结论

我们的研究表明,在我们的三级医疗头颈肿瘤中心,我们显著降低了喉切除术后咽瘘的发生率。通过在手术中常规加用胸大肌肌源性皮瓣覆盖咽缺损,我们大幅且显著地降低了患者的发病率和死亡率,缩短了住院时间,为医疗保健系统节省了大量资金。

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