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强直性脊柱炎与结节病——巧合还是关联?病例报告及文献综述

Ankylosing spondylitis and sarcoidosis--coincidence or association? Case report and review of the literature.

作者信息

Stucki G, von Felten A, Speich R, Michel B A

机构信息

Department of Rheumatology and Physical Therapy, University Hospital, Zurich, Switzerland.

出版信息

Clin Rheumatol. 1992 Sep;11(3):436-9. doi: 10.1007/BF02207214.

Abstract

We report a 25-year-old woman presenting with sarcoidosis and bilateral sacroiliitis. Her sarcoidosis related symptoms (malaise, cough and dyspnoea) improved dramatically under treatment with steroids but severe back pain persisted. Only seven similar cases have been described over the last 40 years and the question of a possible association between the two diseases has been raised. However, prevalence data from the literature and the apparent lack of genetic links are better arguments for coincidence than for association.

摘要

我们报告了一名25岁患有结节病和双侧骶髂关节炎的女性。她的结节病相关症状(不适、咳嗽和呼吸困难)在接受类固醇治疗后显著改善,但严重的背痛仍然存在。在过去40年中,仅描述了7例类似病例,两种疾病之间可能存在关联的问题也已被提出。然而,文献中的患病率数据以及明显缺乏遗传联系,更支持两者是巧合而非关联的观点。

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