Liou L B, Chen T C
Division of Rheumatology, Allergy and Clinical Immunology, Chang Gung Memorial Hospital, Kwei-san, Tao-yuan, Taiwan.
Clin Rheumatol. 1998;17(5):412-5. doi: 10.1007/BF01450906.
We report a case of a patient suffering from enlargement of multiple lymph nodes and low back pain for one year. The diagnosis of ankylosing spondylitis was made by bilateral sacroilitis and HLA-B27 positivity. Lymph nodes biopsy revealed lymphoid hyperplasia. No other cause for the lymphadenopathy was found after a thorough study. Furthermore, high serum IgA and C-reactive protein which were most likely related to active ankylosing spondylitis existed together with lymph node enlargement. Therefore, it was a case of ankylosing spondylitis associated with generalised lymphadenopathy which was the first reported in an oriental person. Several other possible cases also existed. We suggested that ankylosing spondylitis should be considered for young adult patients with lymphadenopathy.
我们报告一例患者，其多个淋巴结肿大且下背痛一年。通过双侧骶髂关节炎和HLA - B27阳性确诊为强直性脊柱炎。淋巴结活检显示淋巴组织增生。经过全面检查，未发现其他导致淋巴结病的原因。此外，高血清IgA和C反应蛋白很可能与活动性强直性脊柱炎有关，同时伴有淋巴结肿大。因此，这是一例强直性脊柱炎合并全身淋巴结肿大的病例，在东方人中属首次报道。其他一些可能的病例也存在。我们建议，对于有淋巴结肿大的年轻成年患者应考虑强直性脊柱炎。
