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幼年和成年太攀蛇(盾鳞棘背蛇)毒液的生物学特性。

The biological properties of venoms from juvenile and adult taipan (Oxyuranus scutellatus) snakes.

作者信息

Tan N H, Armugam A, Mirtschin P J

机构信息

Department of Biochemistry, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Comp Biochem Physiol B. 1992 Nov;103(3):585-8. doi: 10.1016/0305-0491(92)90375-2.

Abstract
  1. The biological properties of four venom pooled samples from adult taipan (Oxyuranus scutellatus) snakes and one pooled venom sample from six juvenile taipan snakes (11 months old) were compared. 2. The intravenous LD50 (median lethal dose), procoagulant activity and enzymatic activities of the juvenile venom were not significantly different from those of the adult venoms. 3. The juvenile and adult venoms exhibited similar polyacrylamide gel electrophoretic (PAGE) and SDS-PAGE patterns, indicating that they possessed a similar protein composition. 4. The results suggest that there is no significant age-dependency in the biological properties of taipan venom.
摘要
  1. 比较了成年太攀蛇(盾鳞棘背蛇)的四个毒液混合样本和六个幼年太攀蛇(11个月大)的一个毒液混合样本的生物学特性。2. 幼年毒液的静脉注射半数致死量(LD50)、促凝血活性和酶活性与成年毒液的这些指标没有显著差异。3. 幼年和成年毒液呈现出相似的聚丙烯酰胺凝胶电泳(PAGE)和SDS-PAGE图谱,表明它们具有相似的蛋白质组成。4. 结果表明,太攀蛇毒液的生物学特性不存在显著的年龄依赖性。

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