Williams C J, Christian J C, Norton J A
Department of Medical Genetics, Indiana University School of Medicine, Indianapolis.
Comput Methods Programs Biomed. 1992 Jul;38(2-3):167-76. doi: 10.1016/0169-2607(92)90084-k.
We discuss the program, TWINAN90, which can perform several different types of analysis of twin data. TWINAN90 incorporates the ANOVA-based twin analyses from the TWINAN twin analysis program, and also includes maximum likelihood estimation of parameters from three path models. Another feature of TWINAN90 is the optional output of a pedigree file which can be read by the quantitative genetics package FISHER. The diagnostic features of the program make TWINAN90 useful also for preliminary analyses prior to the use of more sophisticated modeling procedures which are available in packages such as LISREL and FISHER. An annotated printout from TWINAN90 is presented to illustrate the statistical analyses performed in the program.
我们讨论了TWINAN90程序,它可以对双胞胎数据进行几种不同类型的分析。TWINAN90整合了TWINAN双胞胎分析程序中基于方差分析的双胞胎分析,还包括来自三种路径模型的参数最大似然估计。TWINAN90的另一个特点是可选择输出系谱文件,该文件可由数量遗传学软件包FISHER读取。该程序的诊断功能使TWINAN90在使用LISREL和FISHER等软件包中更复杂的建模程序之前进行初步分析时也很有用。本文给出了TWINAN90的注释打印输出,以说明该程序中执行的统计分析。