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阿尔茨海默病和亨廷顿病患者图形记忆中的侵入性错误。

Intrusion errors in the figural memory of patients with Alzheimer's and Huntington's disease.

作者信息

Jacobs D, Salmon D P, Tröster A I, Butters N

机构信息

University of California, San Diego, USA.

出版信息

Arch Clin Neuropsychol. 1990;5(1):49-57.

Abstract

The tendency of patients with dementia of the Alzheimer type (DAT) and Huntington's disease (HD) to produce prior-item intrusion errors on a figural memory task was assessed. Patients' and elderly control subjects' immediate recall of figures from the Visual Reproduction Test (VRT) of the Wechsler Memory Scale (WMS) was scored for the presence of prior-figure intrusion errors (i.e., characteristics unique to one figure included in the reproduction of a subsequent figure). Results indicate that both patient groups produced more prior-figure intrusion errors than did the NC group, and that DAT patients made significantly more intrusion errors in their reproductions than did HD patients matched for overall severity of dementia. These data suggest that prior-item intrusion errors are evident on figural as well as on verbal memory tasks and that DAT patients are more likely to produce such errors than are equally demented patients with a "subcortical" dementia.

摘要

对阿尔茨海默型痴呆(DAT)患者和亨廷顿舞蹈症(HD)患者在图形记忆任务中产生先前项目侵入错误的倾向进行了评估。对患者和老年对照受试者在韦氏记忆量表(WMS)视觉再现测验(VRT)中对图形的即时回忆进行评分,以确定是否存在先前图形侵入错误(即一个图形的独特特征包含在后续图形的再现中)。结果表明,两个患者组产生的先前图形侵入错误均多于正常对照组,并且在痴呆总体严重程度相匹配的情况下,DAT患者在再现中产生的侵入错误显著多于HD患者。这些数据表明,先前项目侵入错误在图形记忆任务和言语记忆任务中均很明显,并且与患有“皮质下”痴呆且痴呆程度相同的患者相比,DAT患者更有可能产生此类错误。

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