[乳糜泻与自身免疫性疾病或全身性疾病。6例报告及文献复习]
[Celiac disease and autoimmune diseases or systemic disease. Six cases and a review of the literature].
作者信息
Delbrel Xavier, Le-Bougeant Patrick, Etienne Gabriel, Blanco Patrick, Beylot-Barry Marie, Amouretti Michel, Mercie Patrick, Longy-Boursier Maïté
机构信息
Service des Maladies du Sang, Centre François-Magendie, CHU du Haut-Lévêque, 33604 Pessac.
出版信息
Ann Med Interne (Paris). 2003 Sep;154(4):197-204.
BACKGROUND
Celiac disease is an autoimmune disorder which may be associated with another autoimmune or systemic disease.
OBJECTIVE
To determine the links between autoimmune diseases and celiac disease.
PATIENTS AND METHODS
Among 31 patients with a celiac disease, we selected those who had another autoimmune or systemic disease.
RESULTS
We report 6 patients with such disease association: 3 with autoimmune thyroiditis including one also with Grave's disease, 2 with systemic lupus erythematosus including one also with insulin-dependent diabetes mellitus, and 1 with temporal arteritis.
CONCLUSION
The link between celiac disease and autoimmune thyroiditis or insulin-dependent diabetes mellitus seems to be real but many discrepancies are observed for the other autoimmune diseases. After a literature review, we suggest a summary of effective associations between celiac disease and autoimmune or systemic diseases.
背景
乳糜泻是一种自身免疫性疾病，可能与另一种自身免疫性或全身性疾病相关。
目的
确定自身免疫性疾病与乳糜泻之间的联系。
患者与方法
在31例乳糜泻患者中，我们挑选出患有另一种自身免疫性或全身性疾病的患者。
结果
我们报告了6例有此类疾病关联的患者：3例患有自身免疫性甲状腺炎，其中1例还患有格雷夫斯病；2例患有系统性红斑狼疮，其中1例还患有胰岛素依赖型糖尿病；1例患有颞动脉炎。
结论
乳糜泻与自身免疫性甲状腺炎或胰岛素依赖型糖尿病之间的联系似乎是真实存在的，但在其他自身免疫性疾病方面观察到许多差异。经过文献综述，我们提出了乳糜泻与自身免疫性或全身性疾病之间有效关联的总结。
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