Godart Nathalie T, Flament Martine F, Curt Florence, Perdereau Fabienne, Lang François, Venisse Jean Luc, Halfon Olivier, Bizouard Paul, Loas Gwenolé, Corcos Maurice, Jeammet Philippe, Fermanian Jacques
Department of Psychiatry, Institut Mutualiste Montsouris, 42 boulevard Jourdan, 75014, Paris, France.
Psychiatry Res. 2003 Mar 25;117(3):245-58. doi: 10.1016/s0165-1781(03)00038-6.
Women who were referred with an eating disorder (ED) were compared with a matched normal control group to answer the following questions: What are the frequencies of anxiety disorders in cases of anorexia and bulimia nervosa diagnosed according to DSM-IV criteria? Are anxiety disorders significantly more frequent among women with an eating disorder than among women from the community? We assessed the frequencies of six specific anxiety disorders among 271 women with a current diagnosis of anorexia or bulimia nervosa and 271 controls, using the Mini-International Neuropsychiatric Interview, French DSM-IV version. A lifetime comorbidity with at least one anxiety disorder was found in 71% of both the anorexic and the bulimic subjects, significantly higher than the percentage of controls with an anxiety disorder. The prevalence was significantly higher in the eating disorder groups than in controls for most types of anxiety disorder, and between 41.8 and 53.3% of comorbid cases had an anxiety disorder preceding the onset of the eating disorder. Anxiety disorders are significantly more frequent in subjects with eating disorders than in volunteers from the community, a finding that has important etiological and therapeutic implications.
将患有饮食失调症(ED)的女性与匹配的正常对照组进行比较,以回答以下问题:根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准诊断的神经性厌食症和神经性贪食症病例中,焦虑症的发生率是多少?饮食失调症女性中的焦虑症发生率是否显著高于社区女性?我们使用法国DSM-IV版的迷你国际神经精神病学访谈,评估了271名目前诊断为神经性厌食症或神经性贪食症的女性以及271名对照组中六种特定焦虑症的发生率。在神经性厌食症和神经性贪食症患者中,分别有71%的人存在至少一种焦虑症的终生共病情况,显著高于有焦虑症的对照组的比例。大多数类型的焦虑症在饮食失调症组中的患病率显著高于对照组,并且41.8%至53.3%的共病病例在饮食失调症发病之前就已患有焦虑症。饮食失调症患者中的焦虑症发生率显著高于社区志愿者,这一发现具有重要的病因学和治疗意义。