死海古卷羊皮纸氨基酸的改变。

Modification in amino acids of Dead Sea Scroll Parchments.

作者信息

Sobel H, Ajie H

机构信息

Institute of Geophysics and Planetary Physics (IGPP), University of California, Los Angeles 90024.

出版信息

Free Radic Biol Med. 1992 Dec;13(6):701-2. doi: 10.1016/0891-5849(92)90044-h.

DOI:10.1016/0891-5849(92)90044-h

PMID:1459488

Abstract

Fragments of Dead Sea Scroll Parchments were extracted for collagen and subjected to amino acid analysis. In modern parchment samples, 90% or more of the protein could be extracted in hot aqueous solution as collagen. In the ancient specimens, 70% or less was extractable. The hot-solution insoluble material was analyzed for collagen. In the soluble extract, the quantity of tyrosine, histidine, and methionine was reduced. Dityrosine was detected. The need to extend such studies is discussed.

摘要

提取了死海古卷羊皮纸碎片中的胶原蛋白，并对其进行氨基酸分析。在现代羊皮纸样本中，90%或更多的蛋白质可以作为胶原蛋白在热的水溶液中被提取出来。在古代样本中，可提取的比例为70%或更低。对热溶液不溶性物质进行了胶原蛋白分析。在可溶性提取物中，酪氨酸、组氨酸和蛋氨酸的含量减少。检测到了二酪氨酸。讨论了扩展此类研究的必要性。