Skurnik Y, von Der Walde J, Bandel D
Dept. of Medicine A, Kaplan Hospital, Rehovot.
Harefuah. 1992 Oct;123(7-8):262-3, 306.
Sweet's syndrome is an uncommon and dramatic skin disease associated with systemic symptoms such as fever, headache and arthralgia. Since it is also accompanied by an increased erythrocyte sedimentation rate and leukocytosis, it may be confused with severe systemic infections and other systemic illnesses. We describe a 30-year-old woman who presented with typical features of the disease. They included high fever, headache, sore throat, increased sedimentation rate, and a painful violaceous, nodular and papular rash on her limbs and upper trunk. Histologic features included dense neutrophilic infiltration and edema of the dermis, with foci of leukocytoclasia, but without leukocytoclastic vasculitis. There was a dramatic repose to treatment with prednisone.
斯威特综合征是一种罕见且症状明显的皮肤病，常伴有发热、头痛和关节痛等全身症状。由于它还伴有红细胞沉降率升高和白细胞增多，可能会与严重的全身感染及其他全身性疾病相混淆。我们报告一名30岁女性，她表现出该病的典型特征，包括高热、头痛、咽痛、血沉加快，以及四肢和上躯干出现疼痛性紫红色结节及丘疹性皮疹。组织学特征包括真皮层密集的中性粒细胞浸润和水肿，伴有白细胞破碎现象，但无白细胞破碎性血管炎。使用泼尼松治疗后病情显著缓解。
