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酷似暴发性酒渣鼻的面部斯威特综合征。

Facial Sweet's syndrome mimicking rosacea fulminans.

作者信息

Anavekar Namrata S, Williams Richard, Chong Alvin H

机构信息

Department of Dermatology, St Vincent's Hospital, Melbourne, Victoria, Australia.

出版信息

Australas J Dermatol. 2007 Feb;48(1):50-3. doi: 10.1111/j.1440-0960.2007.00334.x.

Abstract

A 36-year-old man presented with a non-pruritic, erythematous facial rash with peri-oral and peri-orbital sparing. The initial clinicopathological diagnosis was rosacea fulminans, which was treated with 25 mg oral prednisolone and cephalexin. The patient re-presented 1 week later with exacerbation of his rash in addition to constitutional symptoms of fever and malaise. A further skin biopsy was taken and the marked neutrophilic infiltrate in the absence of vasculitis made the diagnosis of Sweet's syndrome (acute febrile neutrophilic dermatosis). High-dose prednisolone (50 mg daily), topical hydrocortisone cream and ichthammol in zinc ointment were commenced with rapid clinical improvement. This case highlights the importance of considering Sweet's syndrome as a differential diagnosis when presented with a facial eruption.

摘要

一名36岁男性出现面部皮疹,无瘙痒,呈红斑性,口周和眶周未累及。最初的临床病理诊断为暴发性酒渣鼻,给予25毫克口服泼尼松龙和头孢氨苄治疗。1周后患者再次就诊,皮疹加重,伴有发热和不适等全身症状。再次进行皮肤活检,在无血管炎的情况下有明显的中性粒细胞浸润,诊断为Sweet综合征(急性发热性中性粒细胞性皮肤病)。开始使用大剂量泼尼松龙(每日50毫克)、外用氢化可的松乳膏和鱼石脂锌膏,临床症状迅速改善。该病例强调了在出现面部皮疹时将Sweet综合征作为鉴别诊断的重要性。

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