Muniz Iracema Augusta Carvalho Cortez, Netto Abimael Aranha, Gonçalves Vanda Maria Gimenes
Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Arq Neuropsiquiatr. 2003 Sep;61(3B):808-15. doi: 10.1590/s0004-282x2003000500020. Epub 2003 Oct 28.
This study aimed to evaluate the cerebral blood flow of full term small-for-gestational age newborns, using cranial ultrasound Doppler at birth. This study was performed at CAISM/UNICAMP (Tertiary Health Center for Women). Sixty term newborns were selected and divided in two groups: appropriate-for-gestational age (AGA) (36 neonates) and small-for-gestational age (SGA) (24 neonates). Cranial ultrasound Doppler evaluation was performed on both groups, between 24 and 48 hours after birth. Cerebral blood flow velocity (CBFV) was lower in the small-for-gestational age group, in the anterior cerebral artery (ACA). Doppler measurements were different statistically between the groups only for values related to peak systolic flow velocity (PSFV) and mean flow velocity (MFV) in the ACA. There was no significant difference for any evaluated parameters of flow velocity in the middle cerebral artery (MCA). It was concluded that SGA newborns showed PSFV and MFV significantly reduced only in the ACA. Weight/gestational age, neonatal polycythemia and mean arterial blood pressure values were statistically related to MFV in the ACA. In presence of fetal suffering, mean arterial blood pressure values and smoking in the pregnancy were statistically related to MFV in the MCA.
本研究旨在通过出生时的头颅超声多普勒评估足月小于胎龄新生儿的脑血流情况。本研究在CAISM/UNICAMP（妇女三级保健中心）进行。选取60名足月新生儿并分为两组：适于胎龄儿（AGA）（36名新生儿）和小于胎龄儿（SGA）（24名新生儿）。在出生后24至48小时内对两组进行头颅超声多普勒评估。小于胎龄儿组大脑前动脉（ACA）的脑血流速度（CBFV）较低。两组之间多普勒测量值在统计学上仅在与ACA的收缩期峰值流速（PSFV）和平均流速（MFV）相关的值上存在差异。大脑中动脉（MCA）流速的任何评估参数均无显著差异。得出的结论是，SGA新生儿仅在ACA中表现出PSFV和MFV显著降低。体重/胎龄、新生儿红细胞增多症和平均动脉血压值与ACA中的MFV在统计学上相关。在存在胎儿窘迫的情况下，平均动脉血压值和孕期吸烟与MCA中的MFV在统计学上相关。
