人中耳的计算机集成有限元建模

Computer-integrated finite element modeling of human middle ear.

作者信息

Sun Q, Gan R Z, Chang K-H, Dormer K J

机构信息

School of Aerospace and Mechanical Engineering, The University of Oklahoma, 865 Asp Avenue, Room 200, Norman, OK 73019, USA.

出版信息

Biomech Model Mechanobiol. 2002 Oct;1(2):109-22. doi: 10.1007/s10237-002-0014-z.

DOI:10.1007/s10237-002-0014-z

PMID:14595544

Abstract

The objective of this study was to produce an improved finite element (FE) model of the human middle ear and to compare the model with human data. We began with a systematic and accurate geometric modeling technique for reconstructing the middle ear from serial sections of a freshly frozen temporal bone. A geometric model of a human middle ear was constructed in a computer-aided design (CAD) environment with particular attention to geometry and microanatomy. Using the geometric model, a working FE model of the human middle ear was created using previously published material properties of middle ear components. This working FE model was finalized by a cross-calibration technique, comparing its predicted stapes footplate displacements with laser Doppler interferometry measurements from fresh temporal bones. The final FE model was shown to be reasonable in predicting the ossicular mechanics of the human middle ear.

摘要

本研究的目的是建立一个改进的人中耳有限元（FE）模型，并将该模型与人体数据进行比较。我们首先采用一种系统且精确的几何建模技术，从新鲜冷冻颞骨的连续切片中重建中耳。在计算机辅助设计（CAD）环境中构建了一个人中耳的几何模型，特别关注几何形状和显微解剖结构。利用该几何模型，根据先前发表的中耳部件材料特性创建了一个人中耳的工作FE模型。通过交叉校准技术对该工作FE模型进行了优化，即将其预测的镫骨足板位移与新鲜颞骨的激光多普勒干涉测量结果进行比较。最终的FE模型在预测人中耳听骨力学方面表现合理。