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胰腺/肾脏移植:终末期肾病和1型糖尿病患者的新希望。

Pancreas/kidney transplantation: new hope for patients with end stage renal disease and type 1 diabetes.

作者信息

Wright Liz, Shelton Colleen

机构信息

Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, Ontario.

出版信息

CANNT J. 2003 Jul-Sep;13(3):60-5.

Abstract

For kidney transplant recipients with type 1 diabetes, there are ongoing risks and consequence that can complicate the quality of life after transplantation and present significant challenges to the patient and health care team. There is now an opportunity for those patients with type 1 diabetes and renal failure to treat both conditions with combined pancreas/kidney (P/K) transplantation. It must be emphasized that P/K transplantation is not a cure for renal failure and diabetes, rather, it is a treatment option. Successful pancreas transplantation will eliminate the need for insulin therapy and normalize glucose metabolism, which can greatly improve quality of life. This clinical article will present an overview of the P/K transplantation process, discuss the important role of the dialysis health care professional, and outline the experience of the Multi Organ Transplant (MOT) program of the Toronto General Hospital (TGH), University Health Network (UHN), Toronto, Ontario.

摘要

对于1型糖尿病肾移植受者而言,移植后存在持续的风险和后果,可能会使生活质量复杂化,并给患者和医疗团队带来重大挑战。目前,1型糖尿病合并肾衰竭的患者有机会通过胰肾联合移植(P/K)来治疗这两种疾病。必须强调的是,P/K移植并非肾衰竭和糖尿病的治愈方法,而是一种治疗选择。成功的胰腺移植将消除胰岛素治疗的需求,并使糖代谢正常化,这可极大地改善生活质量。本文将概述P/K移植过程,讨论透析医疗专业人员的重要作用,并概述安大略省多伦多大学健康网络(UHN)多伦多总医院(TGH)多器官移植(MOT)项目的经验。

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