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溴隐亭诱导的小鼠着床失败:种公鼠未能保护妊娠。

Bromocriptine-induced implantation failure in mice: failure of the stud male to protect pregnancy.

作者信息

Archunan G, Dominic C J

机构信息

Department of Zoology, Banaras Hindu University, Varanasi, India.

出版信息

Indian J Exp Biol. 1992 Jul;30(7):648-9.

PMID:1459639
Abstract

The presence of the stud male failed to prevent implantation failure in newly inseminated females induced by administration of bromocriptine. This is in contrast with the ability of the stud male to prevent implantation failure in females induced by alien male exposure, and nutritional stress. Since bromocriptine is a potent inhibitor of hypophysial prolactin release by virtue of its stimulatory effect on hypothalamic dopaminergic activity, the results suggest that the stud male-originating luteotrophic stimulus is incapable of overriding the dopaminergic activity in bromocriptine-treated females.

摘要

种公鼠的存在未能阻止因给予溴隐亭而导致的新受精雌性大鼠的着床失败。这与种公鼠阻止因接触陌生雄鼠和营养应激而导致的雌性大鼠着床失败的能力形成对比。由于溴隐亭凭借其对下丘脑多巴胺能活性的刺激作用而成为垂体催乳素释放的强效抑制剂,这些结果表明,来自种公鼠的促黄体生成刺激无法克服溴隐亭处理过的雌性大鼠中的多巴胺能活性。

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Bromocriptine-induced implantation failure in mice: failure of the stud male to protect pregnancy.溴隐亭诱导的小鼠着床失败:种公鼠未能保护妊娠。
Indian J Exp Biol. 1992 Jul;30(7):648-9.
2
Stud male-induced protection of implantation in food-deprived mice: masking effect of an artificial scent on pheromonal odour.雄性小鼠诱导的食物剥夺小鼠着床保护作用:人工气味对信息素气味的掩盖效应
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Failure of familiar males to prevent alien male-induced implantation block (the Bruce effect) in laboratory mice.在实验室小鼠中,熟悉的雄性未能阻止外来雄性诱导的着床阻断(布鲁斯效应)。
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