Shrivastava S, Subramanyan K, Tandon R
Department of Cardiology, All India Institute of Medical Sciences, New Delhi.
Indian J Pediatr. 1992 Sep-Oct;59(5):579-83. doi: 10.1007/BF02832994.
Thirty patients below the age of 15 years (range 8-1/2 to 15 years, mean 11.8 years) have been studied for the severity of rheumatic mitral regurgitation. Moderately severe to severe pulmonary venous hypertension was found in 76.6% and pulmonary arterial hypertension in 60%. Left ventricular volumes could be calculated in 13 patients. The end-diastolic volume was elevated in 11 and the endsystolic volume in 12 cases. The regurgitant fraction, calculated in nine patients was 0.6 or more in seven cases. The clinical and hemodynamic severity of mitral regurgitation in children was identical to that seen in adults in the absence of active rheumatic carditis. Children with dominant rheumatic mitral regurgitation can develop congestive failure on the basis of valvar damage per se.
对30名15岁以下（年龄范围8.5至15岁，平均11.8岁）的患者进行了风湿性二尖瓣反流严重程度的研究。发现76.6%的患者存在中度至重度肺静脉高压，60%的患者存在肺动脉高压。13名患者的左心室容积可以计算。11例患者舒张末期容积升高，12例患者收缩末期容积升高。9名患者计算出的反流分数，7例为0.6或更高。在没有活动性风湿性心肌炎的情况下，儿童二尖瓣反流的临床和血流动力学严重程度与成人所见相同。以瓣膜损害本身为基础，以风湿性二尖瓣反流为主的儿童可发生充血性心力衰竭。
