Kílícaslan Z, Oztürk F, Sarimurat N, Cuhadaroglu C, Caglar E, Erem A
Chest Department, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
Int J Tuberc Lung Dis. 2003 Nov;7(11):1059-63.
Twenty-four public tuberculosis dispensaries in Istanbul.
To investigate microscopic examination of new pulmonary tuberculosis (TB) cases and treatment outcomes of smear-positive cases.
A retrospective analysis of 12572 new pulmonary tuberculosis cases between 1998 and 2000.
Microscopic examination of sputum smears of all patients and treatment outcomes of smear-positive cases were evaluated.
Of 12572 new TB cases registered between 1998 and 2000, 78.1% (n = 9822) were pulmonary and 21.9% (n = 2750) were extra-pulmonary TB cases. Of 9822 new pulmonary TB cases, 5438 (55.4%) were sputum smear-positive and 2154 (21.9%) had no sputum examination. In smear-positive pulmonary cases, treatment outcomes were classified as follows: 2521 (46.4%) cured, 1926 (35.4%) treatment completed, 128 (2.4%) treatment failure, 514 (9.4%) default, 260 (4.8%) transfer out and 72 (1.3%) died. Treatment success was 81.8% (n = 4447). Between 1998 and 2000, the smear-positive case rate improved from 47.5% to 61.5% and the cure rate improved from 41.8% to 51.1%.
The microscopic diagnosis and cure rates are low in Istanbul dispensaries. The laboratories should be re-organised and directly observed treatment should be performed.
伊斯坦布尔的24家公共结核病诊疗所。
调查新发性肺结核病例的显微镜检查及涂片阳性病例的治疗结果。
对1998年至2000年间12572例新发性肺结核病例进行回顾性分析。
评估所有患者痰液涂片的显微镜检查及涂片阳性病例的治疗结果。
在1998年至2000年间登记的12572例新发性结核病病例中，78.1%（n = 9822）为肺结核病例，21.9%（n = 2750）为肺外结核病例。在9822例新发性肺结核病例中，5438例（55.4%）痰液涂片呈阳性，2154例（21.9%）未进行痰液检查。在涂片阳性的肺结核病例中，治疗结果分类如下：2521例（46.4%）治愈，1926例（35.4%）完成治疗，128例（2.4%）治疗失败，514例（9.4%）中断治疗，260例（4.8%）转出，72例（1.3%）死亡。治疗成功率为81.8%（n = 4447）。1998年至2000年间，涂片阳性病例率从47.5%提高到61.5%，治愈率从41.8%提高到51.1%。
伊斯坦布尔诊疗所的显微镜诊断率和治愈率较低。应重新组织实验室并实施直接观察治疗。
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