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模拟海马体和新皮质对识别记忆的贡献:一种互补学习系统方法。

Modeling hippocampal and neocortical contributions to recognition memory: a complementary-learning-systems approach.

作者信息

Norman Kenneth A, O'Reilly Randall C

机构信息

University of Colorado at Boulder, Department of Psychology, Boulder, CO, USA.

出版信息

Psychol Rev. 2003 Oct;110(4):611-46. doi: 10.1037/0033-295X.110.4.611.

DOI:10.1037/0033-295X.110.4.611
PMID:14599236
Abstract

The authors present a computational neural-network model of how the hippocampus and medial temporal lobe cortex (MTLC) contribute to recognition memory. The hippocampal component contributes by recalling studied details. The MTLC component cannot support recall, but one can extract a scalar familiarity signal from MTLC that tracks how well a test item matches studied items. The authors present simulations that establish key differences in the operating characteristics of the hippocampal-recall and MTLC-familiarity signals and identify several manipulations (e.g., target-lure similarity, interference) that differentially affect the 2 signals. They also use the model to address the stochastic relationship between recall and familiarity and the effects of partial versus complete hippocampal lesions on recognition.

摘要

作者提出了一个关于海马体和内侧颞叶皮质(MTLC)如何对识别记忆做出贡献的计算神经网络模型。海马体部分通过回忆所学细节来发挥作用。MTLC部分无法支持回忆,但可以从MTLC中提取一个标量熟悉度信号,该信号可追踪测试项目与所学项目的匹配程度。作者进行了模拟,确定了海马体回忆信号和MTLC熟悉度信号在操作特性上的关键差异,并识别了几种不同程度影响这两种信号的操作(例如,目标-诱饵相似性、干扰)。他们还使用该模型来探讨回忆与熟悉度之间的随机关系,以及部分或完全海马体损伤对识别的影响。

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Modeling hippocampal and neocortical contributions to recognition memory: a complementary-learning-systems approach.模拟海马体和新皮质对识别记忆的贡献:一种互补学习系统方法。
Psychol Rev. 2003 Oct;110(4):611-46. doi: 10.1037/0033-295X.110.4.611.
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Recollection and familiarity exhibit dissociable similarity gradients: a test of the complementary learning systems model.回忆与熟悉度呈现出可分离的相似性梯度:对互补学习系统模型的一项测试。
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Under what conditions is recognition spared relative to recall after selective hippocampal damage in humans?在人类选择性海马损伤后,相对于回忆而言,识别在何种条件下得以保留?
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Neuropsychologia. 2007 Mar 25;45(6):1232-46. doi: 10.1016/j.neuropsychologia.2006.10.005. Epub 2006 Nov 30.

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