Volkow N D, Tancredi L
Department of Psychiatry, Brookhaven National Laboratories, Upton, N.Y. 11973.
J Clin Psychiatry. 1992 Nov;53 Suppl:26-8.
Over the past 10 years several studies have been conducted in psychiatric and neurologic patients with single photon emission computed tomography (SPECT) to determine if patterns of brain dysfunction exist that characterize the different mental diseases. Although there has not been any finding that can be referred to as specific for a particular disease, SPECT studies have been able to demonstrate evidence of brain dysfunction in patients who, when tested with other means, showed no evidence of brain abnormalities. In this manuscript, the current and future applications of SPECT in the clinical practice of psychiatry are analyzed.
在过去10年里,针对精神科和神经科患者开展了多项单光子发射计算机断层扫描(SPECT)研究,以确定是否存在表征不同精神疾病的脑功能障碍模式。尽管尚未有任何发现可被称为特定疾病所特有,但SPECT研究已能够证明,在通过其他手段检测时未显示脑异常证据的患者中存在脑功能障碍的证据。在本手稿中,分析了SPECT在精神病学临床实践中的当前及未来应用。