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龙葵干燥果实对四氯化碳诱导的大鼠肝损伤的影响。

Effect of dried fruits of Solanum nigrum LINN against CCl4-induced hepatic damage in rats.

作者信息

Raju Kuppuswamy, Anbuganapathi Govindaraju, Gokulakrishnan Velusamy, Rajkapoor Balasubramanian, Jayakar Balasundarm, Manian Sellamuthu

机构信息

PG & Research Department of Botany, Kandaswami Kandar's College, Namakkal, Tamil Nadu, India.

出版信息

Biol Pharm Bull. 2003 Nov;26(11):1618-9. doi: 10.1248/bpb.26.1618.

DOI:10.1248/bpb.26.1618
PMID:14600413
Abstract

Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity. The activity was evaluated using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and total bilirubin. The histopathological changes of liver sample in treated animals were compared with respect to control.

摘要

研究了龙葵乙醇提取物对四氯化碳诱导的大鼠肝损伤的保肝活性。该乙醇提取物显示出显著的保肝活性。使用血清天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)和总胆红素等生化参数评估该活性。将治疗组动物肝脏样本的组织病理学变化与对照组进行比较。

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