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非典型分枝杆菌引起的颞骨感染:病例报告及文献复习

Temporal bone infection caused by atypical mycobacterium: case report and review of the literature.

作者信息

Redaelli de Zinis Luca Oscar, Tironi Andrea, Nassif Nader, Ghizzardi Daniela

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Brescia, Italy.

出版信息

Otol Neurotol. 2003 Nov;24(6):843-9. doi: 10.1097/00129492-200311000-00003.

Abstract

OBJECTIVE

To discuss the clinical aspects and management of nontuberculous mycobacteriosis of the temporal bone.

STUDY DESIGN

Case report and review of the literature.

SETTING

University hospital, tertiary referral center.

PATIENT, INTERVENTION, AND RESULTS: The authors describe an uncommon case of nontuberculous mycobacteriosis of the temporal bone in an immunosuppressed 62-year-old woman with facial nerve paralysis caused by disease complication. The case was cured with radical tympanomastoidectomy and prolonged multiple antibiotic therapy.

CONCLUSIONS

Nontuberculous mycobacteriosis should be suspected in immunosuppressed patients with intractable middle ear granulations. Cultural and histologic examinations are the mainstay for diagnosis. Long-standing multiantibiotic therapy together with aggressive surgery should be considered as appropriate management.

摘要

目的

探讨颞骨非结核分枝杆菌病的临床特点及治疗方法。

研究设计

病例报告及文献复习。

研究地点

大学医院,三级转诊中心。

患者、干预措施及结果:作者描述了一例罕见的颞骨非结核分枝杆菌病病例,患者为一名62岁免疫抑制女性,因疾病并发症导致面神经麻痹。该病例经根治性鼓室乳突切除术及长期多种抗生素治疗后治愈。

结论

对于患有顽固性中耳肉芽的免疫抑制患者,应怀疑非结核分枝杆菌病。培养和组织学检查是诊断的主要依据。长期联合使用多种抗生素治疗及积极的手术治疗应被视为合适的治疗方法。

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