• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Complete remission in a patient with recurrent acute myeloid leukemia induced by vaccination with WT1 peptide in the absence of hematological or renal toxicity.

作者信息

Mailänder V, Scheibenbogen C, Thiel E, Letsch A, Blau I W, Keilholz U

出版信息

Leukemia. 2004 Jan;18(1):165-6. doi: 10.1038/sj.leu.2403186.

DOI:10.1038/sj.leu.2403186
PMID:14603333
Abstract
摘要

相似文献

1
Complete remission in a patient with recurrent acute myeloid leukemia induced by vaccination with WT1 peptide in the absence of hematological or renal toxicity.在无血液学或肾脏毒性的情况下，通过接种WT1肽诱导复发急性髓系白血病患者实现完全缓解。
Leukemia. 2004 Jan;18(1):165-6. doi: 10.1038/sj.leu.2403186.
2
Potential of dendritic-cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole-limpet-hemocyanin-pulsed, donor-derived dendritic-cell vaccine for acute myeloid leukemia.WT1肽和钥孔戚血蓝蛋白脉冲处理的供体来源树突状细胞疫苗用于急性髓系白血病，显示了异基因造血干细胞移植后树突状细胞免疫疗法对复发的治疗潜力。
Am J Hematol. 2008 Apr;83(4):315-7. doi: 10.1002/ajh.21127.
3
A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS.一项针对急性髓系白血病（AML）和骨髓增生异常综合征（MDS）患者的肾母细胞瘤基因产物1（WT1）肽疫苗接种的临床和免疫2期试验。
Blood. 2009 Jun 25;113(26):6541-8. doi: 10.1182/blood-2009-02-202598. Epub 2009 Apr 23.
4
Clinical efficacy of WT1 peptide vaccination in patients with acute myelogenous leukemia and myelodysplastic syndrome.WT1肽疫苗接种对急性髓性白血病和骨髓增生异常综合征患者的临床疗效。
Am J Hematol. 2009 May;84(5):314-5. doi: 10.1002/ajh.21387.
5
"Wilms Tumor Protein 1" (WT1) peptide vaccination-induced complete remission in a patient with acute myeloid leukemia is accompanied by the emergence of a predominant T-cell clone both in blood and bone marrow.“Wilms 瘤蛋白 1”（WT1）肽疫苗接种诱导急性髓系白血病患者完全缓解，同时在血液和骨髓中出现优势 T 细胞克隆。
J Immunother. 2011 Jan;34(1):85-91. doi: 10.1097/CJI.0b013e3181f3cc5c.
6
Approaches to the therapy of relapsed acute myeloid leukemia.复发性急性髓系白血病的治疗方法。
Oncology (Williston Park). 1989 Aug;3(8):23-7; discussion 28.
7
WT1 peptide vaccine induces reduction in minimal residual disease in an Imatinib-treated CML patient.WT1 肽疫苗可诱导伊马替尼治疗的 CML 患者微小残留病灶减少。
Eur J Haematol. 2010 Oct;85(4):358-60. doi: 10.1111/j.1600-0609.2010.01497.x. Epub 2010 Aug 30.
8
Induction of complete remission in a patient with acute myeloid leukemia refractory to high-dose chemotherapy through treatment with 5-azacytidine.通过5-氮杂胞苷治疗使一名对大剂量化疗难治的急性髓性白血病患者获得完全缓解。
Leuk Res. 2007 Mar;31(3):407-9. doi: 10.1016/j.leukres.2006.06.017. Epub 2006 Aug 4.
9
WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse: successful maintenance of durable remission.WT1肽疫苗接种用于复发高危的小儿白血病患者异基因干细胞移植后：成功维持持久缓解
Leukemia. 2012 Mar;26(3):530-2. doi: 10.1038/leu.2011.226. Epub 2011 Aug 26.
10
Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy.WT1 肽免疫疗法治疗妇科恶性肿瘤。
Anticancer Res. 2009 Nov;29(11):4779-84.

引用本文的文献

1
JCMM Annual Review on Advances in Biotechnology for the Treatment of Haematological Malignancies: A Review of the Latest In-Patient Developments 2024-2025.《JCMM关于血液恶性肿瘤治疗生物技术进展的年度回顾：2024 - 2025年最新住院治疗进展回顾》
J Cell Mol Med. 2025 Jul;29(13):e70700. doi: 10.1111/jcmm.70700.
2
AML-VAC-XS15-01: protocol of a first-in-human clinical trial to evaluate the safety, tolerability and preliminary efficacy of a multi-peptide vaccine based on leukemia stem cell antigens in acute myeloid leukemia patients.AML-VAC-XS15-01：一项针对急性髓系白血病患者评估基于白血病干细胞抗原的多肽疫苗安全性、耐受性和初步疗效的首次人体临床试验方案。
Front Oncol. 2024 Oct 14;14:1458449. doi: 10.3389/fonc.2024.1458449. eCollection 2024.
3
Immunotherapy Applications for Thymine Dimers and WT1 Antigen in Renal Cancers: A Comparative Statistical Analysis.免疫疗法在肾癌中对胸腺嘧啶二聚体和WT1抗原的应用：一项比较统计分析。
J Pers Med. 2024 May 23;14(6):557. doi: 10.3390/jpm14060557.
4
FusionVAC22_01: a phase I clinical trial evaluating a DNAJB1-PRKACA fusion transcript-based peptide vaccine combined with immune checkpoint inhibition for fibrolamellar hepatocellular carcinoma and other tumor entities carrying the oncogenic driver fusion.FusionVAC22_01：一项I期临床试验，评估基于DNAJB1-PRKACA融合转录本的肽疫苗联合免疫检查点抑制疗法用于治疗纤维板层型肝细胞癌及其他携带致癌驱动融合的肿瘤实体。
Front Oncol. 2024 Mar 28;14:1367450. doi: 10.3389/fonc.2024.1367450. eCollection 2024.
5
Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: Impact of CMV infection and leukemia relapse.异基因造血细胞移植后急性髓系白血病患者 CMV 特异性和 WT1 特异性 T 细胞的不同恢复模式：CMV 感染和白血病复发的影响。
Front Immunol. 2023 Feb 7;13:1027593. doi: 10.3389/fimmu.2022.1027593. eCollection 2022.
6
Immune-Based Therapeutic Interventions for Acute Myeloid Leukemia.急性髓系白血病的免疫治疗干预措施
Cancer Treat Res. 2022;183:225-254. doi: 10.1007/978-3-030-96376-7_8.
7
First-in-human study of WT1 recombinant protein vaccination in elderly patients with AML in remission: a single-center experience.在缓解期老年 AML 患者中进行 WT1 重组蛋白疫苗接种的首次人体研究：单中心经验。
Cancer Immunol Immunother. 2022 Dec;71(12):2913-2928. doi: 10.1007/s00262-022-03202-8. Epub 2022 Apr 27.
8
Evaluating Established Roles, Future Perspectives and Methodological Heterogeneity for Wilms' Tumor 1 (WT1) Antigen Detection in Adult Renal Cell Carcinoma, Using a Novel N-Terminus Targeted Antibody (Clone WT49).使用新型N端靶向抗体（克隆WT49）评估成人肾细胞癌中威尔姆斯瘤1（WT1）抗原检测的既定作用、未来前景和方法学异质性
Biomedicines. 2022 Apr 15;10(4):912. doi: 10.3390/biomedicines10040912.
9
Efficacy and safety of Wilms' tumor 1 helper peptide OCV-501 in elderly patients with acute myeloid leukemia: a multicenter, randomized, double-blind, placebo-controlled phase 2 trial.肾母细胞瘤1辅助肽OCV-501在老年急性髓系白血病患者中的疗效与安全性：一项多中心、随机、双盲、安慰剂对照的2期试验。
Cancer Immunol Immunother. 2022 Jun;71(6):1419-1430. doi: 10.1007/s00262-021-03074-4. Epub 2021 Oct 22.
10
Immunopeptidomics-Guided Warehouse Design for Peptide-Based Immunotherapy in Chronic Lymphocytic Leukemia.免疫肽组学指导慢性淋巴细胞白血病基于肽的免疫治疗的仓库设计。
Front Immunol. 2021 Jul 8;12:705974. doi: 10.3389/fimmu.2021.705974. eCollection 2021.