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过氧化脲和过氧化氢治疗氟斑牙患者的疗效:一项临床试验。

Effectiveness of treatment with carbamide peroxide and hydrogen peroxide in subjects affected by dental fluorosis: a clinical trial.

作者信息

Loyola-Rodriguez Juan Pablo, Pozos-Guillen Amaury de Jesus, Hernandez-Hernandez Felipe, Berumen-Maldonado Rocio, Patiño-Marin Nuria

机构信息

Dental Research Center, San Luis Potosi University, Mexico.

出版信息

J Clin Pediatr Dent. 2003 Fall;28(1):63-7. doi: 10.17796/jcpd.28.1.1q78t43054jk5911.

DOI:10.17796/jcpd.28.1.1q78t43054jk5911
PMID:14604145
Abstract

Dental fluorosis is an endemic dental health problem around the world; so, it is important to develop clinical alternatives that are non-invasive and inexpensive. In this study, nightguard vital bleaching technique (NVBT), using carbamide and hydrogen peroxide as active agents, has shown itself to be effective in whitening teeth affected by dental fluorosis. Carbamide peroxide at 10 and 20% and hydrogen peroxide at 7.5% showed good clinical effectiveness in improving clinical appearence, but it is important to point out that clinical success is only in cases of class 1 to 3 of the Tooth Surface Index of Fluorosis. When comparing 10 and 20% concentrations of carbamide peroxide, there was no difference in the clinical effectiveness (p > 0.05); but when comparing both concentrations of carbamide peroxide against hydrogen peroxide, results showed that carbamide peroxide was more effective in whitening in cases of dental fluorosis, the difference being statistically significant (p < 0.05). NVBT has two advantages: it is a non-invasive technique and the relationship cost/benefit is excellent; only a few patients reported tenderness or mild tooth sensitivity.

摘要

氟斑牙是全球范围内的一种地方性牙齿健康问题;因此,开发无创且低成本的临床替代方法很重要。在本研究中,使用尿素和过氧化氢作为活性剂的夜间护齿美白技术(NVBT)已证明其在美白受氟斑牙影响的牙齿方面是有效的。10%和20%的过氧化脲以及7.5%的过氧化氢在改善临床外观方面显示出良好的临床效果,但需要指出的是,临床成功仅适用于氟斑牙牙齿表面指数1至3级的病例。比较10%和20%浓度的过氧化脲时,临床效果没有差异(p>0.05);但将两种浓度的过氧化脲与过氧化氢进行比较时,结果表明,在氟斑牙病例中,过氧化脲在美白方面更有效,差异具有统计学意义(p<0.05)。NVBT有两个优点:它是一种无创技术,成本效益比极佳;只有少数患者报告有压痛或轻度牙齿敏感。

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