有序、无序与灵活性：基于蛋白质序列的预测

Order, disorder, and flexibility: prediction from protein sequence.

作者信息

Iakoucheva Lilia M, Dunker A Keith

机构信息

The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

出版信息

Structure. 2003 Nov;11(11):1316-7. doi: 10.1016/j.str.2003.10.009.

DOI:10.1016/j.str.2003.10.009

PMID:14604521

Abstract

The new predictor of disordered protein regions (disEMBL) introduced in this issue of Structure represents a computational tool developed to aid structural biologists in the design of protein constructs that avoid disordered protein regions in order to increase the success rate of structure determination.

摘要

本期《结构》杂志中介绍的新型无序蛋白区域预测工具（disEMBL）是一种计算工具，旨在帮助结构生物学家设计避免无序蛋白区域的蛋白质构建体，以提高结构测定的成功率。