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[体外循环心脏手术中细胞外液的评估]

[Assessment of extracellular fluid in cardiac surgery using cardiopulmonary bypass].

作者信息

Hamada Yoshihiro, Kawachi K, Tsunooka N, Nakamura Y, Takano S, Imagawa H, Kadota M

机构信息

Department of Second Surgery, Ehime University School of Medicine, Ehime, Japan.

出版信息

Kyobu Geka. 2003 Nov;56(12):1011-3.

PMID:14608923
Abstract

Extracellular fluid (ECF) was assessed before and after the cardiac surgery using cardiopulmonary bypass (CPB), by means of a bioimpedance spectrum analyzer to see volumes of the fluid based on changes of the impedance to various frequencies. Difference between the levels before and after the operation was divided by body weight to study about a % BW. Simultaneously its relation to the lung compliance [tidal volume/(peak inspiratory pressure-end expiratory pressure)] was studied. Mean age of the 18 patients was 59.1 +/- 19 years old. ECF was assessed before to 24 hours after the operation continuously and once more after 48 hours. Mean CPB time was 165 +/- 52 minutes, and aortic cross clamp time was 121 +/- 4 minutes. A remarkable increase of ECF was noted immediately after the operation, which further increased gradually till arriving at the peak 4 hours after the operation (4.52 +/- 1.8% BW). Then it gradually decreased to 0.641 +/- 2.7% BW 48 hours later. Lung compliance measured at the same time showed the lowest level 6 hours after the operation. It was known that the bioimpedance spectrum analysis is a simple and non-invasive method, which enables to monitor the vital stable before and after the operation.

摘要

在心脏手术(采用体外循环[CPB])前后,通过生物电阻抗谱分析仪评估细胞外液(ECF),以根据不同频率下的阻抗变化来观察该液体的容量。将手术前后的水平差异除以体重,以研究占体重的百分比(%BW)。同时研究其与肺顺应性[潮气量/(吸气峰压 - 呼气末压)]的关系。18例患者的平均年龄为59.1±19岁。在手术前至术后24小时连续评估ECF,并在48小时后再次评估。平均CPB时间为165±52分钟,主动脉阻断时间为121±4分钟。术后立即观察到ECF显著增加,并在术后4小时达到峰值(4.52±1.8%BW)之前逐渐进一步增加。然后在48小时后逐渐降至0.641±2.7%BW。同时测量的肺顺应性在术后6小时显示出最低水平。已知生物电阻抗谱分析是一种简单且无创的方法,能够监测手术前后的生命体征稳定性。

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