Yen Ju-Bei, Chang Kuei-Wen, Wu Tsu-Lan, Kuo An-Jin, Su Lin-Hui
Department of Pediatrics, Chang Gung Children's Hospital, Taipei, Taiwan, ROC.
Chang Gung Med J. 2003 Aug;26(8):611-4.
Shigellosis continues to be an important public health problem in developed countries, since communication in the world village has become more frequent. In addition, this disease is difficult to be prevented because only a small number of bacteria are required to cause infection, and it has exhibited steady trends towards multiple drug resistance. This report describes a 7-month-old female infant with Shigella flexneri sepsis presenting initially with a high fever, watery diarrhea, and dehydration. She was successfully treated with ceftriaxone for 7 days. This case illustrates that Shigella should be included in the differential diagnosis of sepsis associated with diarrhea particularly in young infants traveling to or living in an endemic area. The choice of antimicrobial therapy and the optimal duration for treatment should be carefully evaluated because of the emergence of multidrug-resistant Shigella.
由于地球村的交流日益频繁，志贺氏菌病在发达国家仍是一个重要的公共卫生问题。此外，这种疾病难以预防，因为只需少量细菌就能引发感染，而且它已呈现出对多种药物耐药的稳定趋势。本报告描述了一名7个月大的患弗氏志贺菌败血症的女婴，最初表现为高烧、水样腹泻和脱水。她接受头孢曲松治疗7天，治疗成功。该病例表明，在腹泻相关败血症的鉴别诊断中应考虑志贺氏菌，尤其是对于前往或居住在流行地区的幼儿。由于多重耐药志贺氏菌的出现，应仔细评估抗菌治疗的选择和最佳治疗时长。
