Cahill M T, Kaiser P K, Sears J E, Fekrat S
Duke University Eye Center, Erwin Road, PO Box 3802, Durham, NC 27710, USA.
Br J Ophthalmol. 2003 Nov;87(11):1329-32. doi: 10.1136/bjo.87.11.1329.
Arteriovenous (AV) sheathotomy, a potential treatment for branch retinal vein occlusion (BVO), surgically separates retinal vessels at an AV crossing. Relief of the aetiological obstruction, with resolution of cystoid macular oedema (CMO), may result in improved visual acuity.
A retrospective review of consecutive cases of AV sheathotomy for BVO was undertaken. Eyes were categorised as having resolution (group 1), reduction (group 2), or persistence (group 3) of CMO. Intergroup comparisons were made with regard to preoperative, intraoperative, and postoperative parameters. Preoperative and postoperative visual acuities were compared within each group.
Of the 27 eyes identified, eight (29.6%) had resolution, 14 (51.8%) had reduction, and five (18.6%) had persistence of CMO. Median preoperative visual acuity was similar in all groups (1.0, 1.0, 1.3, respectively; p = 0.29). Overall median follow up was 12.0 months (Q1 = 12.0, Q2 = 22.5). Eyes in group 1 had significantly better median postoperative visual acuity than eyes in groups 2 and 3 (0.6, 1.0, 2.0 respectively; p = 0.01). A significantly higher proportion of eyes in group 1 had visual acuity improvement compared with eyes in the other groups (87.5% v 35.7% and 20.0%; p = 0.03). Median postoperative visual acuity was significantly better than median preoperative visual acuity in group 1 eyes only (p = 0.02). A higher percentage of group 1 eyes had evidence of postoperative retinal perfusion (83.0% v 21.43% and 40.0%; p = 0.16). Postoperative retinal detachment occurred in three eyes (11.1%).
Complete resolution of CMO after AV sheathotomy occurred in one third of patients, and postoperative vision improved significantly in this group. However, in the majority of cases, despite an improvement in CMO, there was no improvement in vision after AV sheathotomy.
动静脉鞘膜切开术是视网膜分支静脉阻塞(BVO)的一种潜在治疗方法,通过手术分离动静脉交叉处的视网膜血管。病因性阻塞的解除以及黄斑囊样水肿(CMO)的消退可能会提高视力。
对连续进行动静脉鞘膜切开术治疗BVO的病例进行回顾性研究。将眼睛分为CMO消退组(第1组)、减轻组(第2组)或持续组(第3组)。对术前、术中和术后参数进行组间比较。比较每组术前和术后的视力。
在确定的27只眼中,8只(29.6%)CMO消退,14只(51.8%)减轻,5只(18.6%)持续存在。所有组术前的中位视力相似(分别为1.0、1.0、1.3;p = 0.29)。总体中位随访时间为12.0个月(第一四分位数 = 12.0,第二四分位数 = 22.5)。第1组眼睛术后的中位视力明显优于第2组和第3组(分别为0.6、1.0、2.0;p = 0.01)。与其他组相比,第1组中视力提高的眼睛比例明显更高(87.5%对35.7%和20.0%;p = 0.03)。仅第1组眼睛术后的中位视力明显优于术前中位视力(p = 0.02)。第1组中有更高比例的眼睛有术后视网膜灌注的证据(83.0%对21.43%和40.0%;p = 0.16)。3只眼(11.1%)发生了术后视网膜脱离。
动静脉鞘膜切开术后,三分之一的患者CMO完全消退,该组患者术后视力显著改善。然而,在大多数情况下,尽管CMO有所改善,但动静脉鞘膜切开术后视力并无改善。