人类胰腺β细胞对链脲佐菌素和四氧嘧啶毒性产生抗性的潜在机制。 - Suppr

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超能文献

Mechanism underlying resistance of human pancreatic beta cells against toxicity of streptozotocin and alloxan.

作者信息

Elsner M, Tiedge M, Lenzen S

机构信息

Institute of Clinical Biochemistry, Hannover Medical School, 30623, Hannover, Germany.

出版信息

Diabetologia. 2003 Dec;46(12):1713-4. doi: 10.1007/s00125-003-1241-2. Epub 2003 Nov 12.

DOI:10.1007/s00125-003-1241-2

PMID:14614558

Abstract

摘要

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本文引用的文献

Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan.

Diabetologia. 2002 Nov;45(11):1542-9. doi: 10.1007/s00125-002-0955-x. Epub 2002 Oct 2.

Human beta cells are exceedingly resistant to streptozotocin in vivo.

Endocrinology. 2002 Jul;143(7):2491-5. doi: 10.1210/endo.143.7.8901.

Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan.

Gen Comp Endocrinol. 2001 Jun;122(3):238-51. doi: 10.1006/gcen.2001.7638.

Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin.

Diabetologia. 2000 Dec;43(12):1528-33. doi: 10.1007/s001250051564.

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells.

Diabetes. 1997 Nov;46(11):1733-42. doi: 10.2337/diab.46.11.1733.

Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.

Mol Med. 1995 Nov;1(7):806-20.

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.

Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9253-6. doi: 10.1073/pnas.91.20.9253.

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression.

J Clin Invest. 1995 Nov;96(5):2489-95. doi: 10.1172/JCI118308.

Pancreatic islet GLUT2 glucose transporter mRNA and protein expression in humans with and without NIDDM.

Diabetes. 1995 Dec;44(12):1369-74. doi: 10.2337/diab.44.12.1369.

Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells.

Diabetologia. 1984 Dec;27(6):587-91. doi: 10.1007/BF00276973.

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