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脾外伤的保守治疗:历史与当前趋势

Conservative management of splenic trauma: history and current trends.

作者信息

Upadhyaya P

机构信息

7c Mohini Road, Dalanwala, 248 001 Dehra Dun, India.

出版信息

Pediatr Surg Int. 2003 Nov;19(9-10):617-27. doi: 10.1007/s00383-003-0972-y. Epub 2003 Nov 12.

Abstract

Evolution of the present-day policy of conservative management of ruptured spleen has been hailed as one of the most notable advances in pediatric surgery. Until 1971, routine splenectomy used to be the sacrosanct treatment for splenic trauma. It was universally believed that non-operative management carried a high mortality of 90 to 100%. Sporadic reports of successful conservative treatment appeared in the early twentieth century, but regrettably, these were ignored. Likewise, experimental studies pointing to the danger of post-splenectomy sepsis were also disregarded. Dominant surgical opinion continued to practice removal of the injured spleen. In 1968, Upadhyaya and Simpson, based on a well-designed clinical analysis of 52 children made a convincing plea for conservative management. In 1971, Upadhyaya et al. presented results of a corroborative experimental study, which provided the conclusive evidence that isolated splenic tears are well tolerated and heal spontaneously by first intention. Seeing the surge of publications that followed this presentation, it becomes apparent that this study constituted the real turning point that changed the world opinion in favour of salvage of the ruptured spleen. By 1979, numerous authors had reported the safety of non-operative management in hundreds of children all over the world. Currently, the policy of routine splenectomy has been universally abandoned; and the reported salvage rate of ruptured spleen is more than 90%. This paper traces the historical perspectives in the management of injured spleen from the times of Aristotle to the present day.

摘要

目前对脾破裂采取保守治疗的政策演变,被誉为小儿外科最显著的进展之一。直到1971年,常规脾切除术一直是脾外伤的神圣治疗方法。人们普遍认为,非手术治疗的死亡率高达90%至100%。20世纪初出现了零星的成功保守治疗报告,但遗憾的是,这些报告被忽视了。同样,指出脾切除术后败血症危险的实验研究也被忽视了。主流的外科观点继续主张切除受伤的脾脏。1968年,Upadhyaya和Simpson基于对52名儿童精心设计的临床分析,令人信服地呼吁采取保守治疗。1971年,Upadhyaya等人发表了一项确证性实验研究的结果,该研究提供了确凿的证据,即孤立的脾破裂能够很好地耐受,并能一期愈合。从这项研究发表后大量的出版物激增可以看出,这项研究构成了真正的转折点,改变了全世界对挽救破裂脾脏的看法。到1979年,许多作者报告了世界各地数百名儿童非手术治疗的安全性。目前,常规脾切除术的政策已被普遍摒弃;据报道,脾破裂的挽救率超过90%。本文追溯了从亚里士多德时代到当今脾损伤治疗的历史观点。

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