在仅乙肝核心抗原抗体阳性的HIV感染者中，乙肝病毒血症持续存在的患病率较低。 - Suppr

Low prevalence of ongoing hepatitis B viremia in HIV-positive individuals with isolated antibody to hepatitis B core antigen.

作者信息

Gandhi Rajesh T, Wurcel Alysse, McGovern Barbara, Lee Hang, Shopis Janet, Corcoran Colleen P, Toner Sarah, Giachetti Christina, Dockter Janel, Sax Paul E, Ukomadu Chinweike

出版信息

J Acquir Immune Defic Syndr. 2003 Dec 1;34(4):439-41. doi: 10.1097/00126334-200312010-00013.

DOI:10.1097/00126334-200312010-00013

PMID:14615664

Abstract

摘要

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Low prevalence of ongoing hepatitis B viremia in HIV-positive individuals with isolated antibody to hepatitis B core antigen.在仅乙肝核心抗原抗体阳性的HIV感染者中，乙肝病毒血症持续存在的患病率较低。

J Acquir Immune Defic Syndr. 2003 Dec 1;34(4):439-41. doi: 10.1097/00126334-200312010-00013.

Isolated antibody to hepatitis B core antigen in individuals infected with HIV-1.

Clin Infect Dis. 2003 Nov 1;37(9):1275-6;; author reply 1277. doi: 10.1086/378896.

HBcAb seropositivity is correlated with poor HIV viremia control in an Italian cohort of HIV/HBV-coinfected patients on first-line therapy.HBcAb 血清学阳性与意大利一线治疗的 HIV/HBV 合并感染患者的 HIV 病毒血症控制不佳相关。

Sci Rep. 2019 Aug 16;9(1):11942. doi: 10.1038/s41598-019-46976-1.

Routine hepatitis B virus DNA testing in human immunodeficiency virus-infected patients with positive hepatitis B core antibody but negative hepatitis B surface antigen is not justified by current evidence.对于乙肝核心抗体阳性但乙肝表面抗原阴性的人类免疫缺陷病毒感染患者，目前的证据并不支持进行常规乙肝病毒DNA检测。

Hepatology. 2010 Mar;51(3):1087-8. doi: 10.1002/hep.23395.

Hepatitis B: Prevalence and occult infection in HIV-infected patients.乙型肝炎：HIV 感染者中的流行情况和隐匿性感染。

Rev Soc Bras Med Trop. 2020 Jan 27;53:e20180533. doi: 10.1590/0037-8682-0533-2018. eCollection 2020.

Patterns of hepatitis B virus infection in Brazilian human immunodeficiency virus infected patients: high prevalence of occult infection and low frequency of lamivudine resistant mutations.巴西人类免疫缺陷病毒感染患者的乙型肝炎病毒感染模式：隐匿性感染的高流行率和拉米夫定耐药突变的低频率

Mem Inst Oswaldo Cruz. 2006 Sep;101(6):655-60. doi: 10.1590/s0074-02762006000600013.

Parenteral exposure to high HIV viremia leads to virus-specific T cell priming without evidence of infection.肠胃外暴露于高HIV病毒血症会导致病毒特异性T细胞启动，但无感染迹象。

Eur J Immunol. 2004 Nov;34(11):3208-15. doi: 10.1002/eji.200424889.

HIV-HBV vaccine escape mutant infection with loss of HBV surface antibody and persistent HBV viremia on tenofovir/emtricitabine without antiviral resistance.在未发生抗病毒耐药的情况下，使用替诺福韦/恩曲他滨治疗时，HIV-HBV 疫苗逃逸突变感染可导致 HBV 表面抗体丧失和持续性 HBV 病毒血症。

J Clin Virol. 2011 Nov;52(3):261-4. doi: 10.1016/j.jcv.2011.07.014. Epub 2011 Aug 12.

Impact of occult hepatitis B virus infection in HIV patients naive for antiretroviral therapy.隐匿性乙型肝炎病毒感染对抗逆转录病毒治疗初治的HIV患者的影响。

AIDS. 2006 Jun 12;20(9):1253-60. doi: 10.1097/01.aids.0000232232.41877.2a.

The role of anti-HBs in hepatitis B reactivation during direct-acting antiviral therapy for chronic hepatitis C.抗-HBs在慢性丙型肝炎直接抗病毒治疗期间乙肝再激活中的作用

Antivir Ther. 2018;23(6):539-542. doi: 10.3851/IMP3259.

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Mortality in relation to hepatitis B virus (HBV) infection status among HIV-HBV co-infected patients in sub-Saharan Africa after immediate initiation of antiretroviral therapy.在撒哈拉以南非洲，接受即刻抗逆转录病毒治疗的 HIV-HBV 合并感染患者中，与乙型肝炎病毒（HBV）感染状态相关的死亡率。

J Viral Hepat. 2021 Apr;28(4):621-629. doi: 10.1111/jvh.13461. Epub 2021 Jan 23.

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.慢性乙型肝炎的预防、诊断和治疗最新进展：美国肝病研究学会2018年乙型肝炎指南

Hepatology. 2018 Apr;67(4):1560-1599. doi: 10.1002/hep.29800.

Isolated Hepatitis B Core Antibody Status Is Not Associated With Accelerated Liver Disease Progression in HIV/Hepatitis C Coinfection.孤立的乙肝核心抗体状态与HIV/丙型肝炎合并感染时肝病进展加速无关。

J Acquir Immune Defic Syndr. 2016 Jul 1;72(3):274-80. doi: 10.1097/QAI.0000000000000969.

Hepatitis B virus coinfection in human immunodeficiency virus-infected patients: a review.人类免疫缺陷病毒感染患者中的乙型肝炎病毒合并感染：综述

World J Gastroenterol. 2014 Oct 28;20(40):14598-614. doi: 10.3748/wjg.v20.i40.14598.

Prevalence, risk factors, and impact of isolated antibody to hepatitis B core antigen and occult hepatitis B virus infection in HIV-1-infected pregnant women.在感染 HIV-1 的孕妇中，孤立的乙型肝炎核心抗原抗体和隐匿性乙型肝炎病毒感染的流行率、危险因素和影响。

Clin Infect Dis. 2013 Jun;56(12):1704-12. doi: 10.1093/cid/cit166. Epub 2013 Mar 13.

Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.初治 HIV 感染患者中乙型肝炎和丙型肝炎病毒感染的流行情况和特征。

Med Microbiol Immunol. 2011 Feb;200(1):39-49. doi: 10.1007/s00430-010-0172-z. Epub 2010 Sep 19.

Long-term serologic follow-up of isolated hepatitis B core antibody in HIV-infected and HIV-uninfected women.对感染HIV和未感染HIV的女性中单纯乙肝核心抗体的长期血清学随访

Clin Infect Dis. 2009 Jul 1;49(1):148-54. doi: 10.1086/599610.

Isolated hepatitis B core antibody is associated with HIV and ongoing but not resolved hepatitis C virus infection in a cohort of US women.在美国一组女性队列中，孤立的乙肝核心抗体与HIV以及持续但未清除的丙型肝炎病毒感染相关。

J Infect Dis. 2007 May 15;195(10):1437-42. doi: 10.1086/515578. Epub 2007 Apr 5.

Update on Hepatitis B and C Coinfection in HIV.HIV合并乙型和丙型肝炎病毒感染的最新情况

Curr Infect Dis Rep. 2005 Jul;7(4):299-308. doi: 10.1007/s11908-005-0063-4.

Association between syphilis, antibodies to herpes simplex virus type 2, and recreational drug use and hepatitis B virus infection in the Women's Interagency HIV Study.女性机构间HIV研究中梅毒、2型单纯疱疹病毒抗体、娱乐性药物使用与乙型肝炎病毒感染之间的关联

Clin Infect Dis. 2004 Nov 1;39(9):1363-70. doi: 10.1086/424879. Epub 2004 Oct 7.

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Low prevalence of ongoing hepatitis B viremia in HIV-positive individuals with isolated antibody to hepatitis B core antigen.

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