Somers C J, Millar B C, Xu J, Moore D P, Moran A M, Maloney C, Keogh B, Murphy P G, Moore J E
Department of Microbiology, The Laboratories, The Adelaide and Meath Hospital, Dublin 24, Ireland, UK.
Clin Microbiol Infect. 2003 Oct;9(10):1048-50. doi: 10.1046/j.1469-0691.2003.00703.x.
This report presents a case of endocarditis due to Haemophilus segnis, which represents a speciation difficulty for the routine laboratory. In this study, a molecular approach provided speciation, which was confirmed phenotypically by a reference laboratory. The use of molecular genotypic analysis is an additional strategy in the investigation of endocarditis. It has applications not only in isolate identification but also in primary detection of infection, particularly in patients whose blood is culture negative by conventional methodologies.
本报告介绍了一例由迟缓嗜血杆菌引起的心内膜炎病例,该菌对于常规实验室来说存在种属鉴定困难。在本研究中,一种分子方法实现了种属鉴定,参考实验室通过表型分析对其进行了确认。分子基因型分析的应用是心内膜炎调查中的一项额外策略。它不仅可用于分离株鉴定,还可用于感染的初步检测,特别是对于那些通过传统方法血培养呈阴性的患者。