Fanourgiakis P, Georgala A, Vekemans M, Daneau D, Heymans C, Aoun M
Laboratoire de Microbiologie et Département des Maladies Infectieuses, Institut Jules Bordet, rue Héger-Bordet 1, 1000 Bruxelles, Belgium.
Clin Microbiol Infect. 2003 Oct;9(10):1068-72. doi: 10.1046/j.1469-0691.2003.00772.x.
This study reviews the clinical manifestations, causes and frequency of Stomatococcus mucilaginosus bacteremia in neutropenic cancer patients. We analyzed retrospectively all clinical and microbiological records of patients with S. mucilaginosus bacteremia. The incidence was compared with that of other pathogens causing bacteremia during neutropenia for the same period. S. mucilaginosus represented 5.9% of bacteremias in our neutropenic patients. Seven patients with hematologic malignancies and one with breast cancer are described. The common clinical presentation was one of sepsis. All patients presented with damaged mucosal barriers as the probable portal of entry, from either stomatitis or enterocolitis. All patients survived.
本研究回顾了中性粒细胞减少的癌症患者中黏性口腔球菌血症的临床表现、病因及发生率。我们对黏性口腔球菌血症患者的所有临床和微生物学记录进行了回顾性分析。将该发生率与同期中性粒细胞减少期间引起菌血症的其他病原体的发生率进行了比较。黏性口腔球菌在我们的中性粒细胞减少患者的菌血症中占5.9%。描述了7例血液系统恶性肿瘤患者和1例乳腺癌患者。常见的临床表现为脓毒症之一。所有患者均表现出黏膜屏障受损,这可能是感染的入口,原因是口腔炎或小肠结肠炎。所有患者均存活。