Bianchi L, Costanzo A, Campione E, Nisticò S, Chimenti S
Department of Dermatology, Tor Vergata University of Rome, Italy.
Clin Exp Dermatol. 2003 Nov;28 Suppl 1:24-6. doi: 10.1046/j.1365-2230.28.s1.8.x.
Skin cancer is the most common malignancy in humans and accounts for one-third of newly diagnosed cancers. Basal cell carcinoma (BCC) is one of the most prevalent and persistent types, and appears in two main histological forms, superficial and nodular. Typical treatments include surgery; however, this may leave scarring, which is undesirable, especially in facial lesions. We report the results of seven individual patients with one or more BCCs (both nodular and superficial) treated with imiquimod 5% cream. Eleven of 13 lesions cleared following daily topical treatment for 10-18 weeks. Any local skin reactions resolved at the end of treatment.
皮肤癌是人类最常见的恶性肿瘤，占新诊断癌症的三分之一。基底细胞癌（BCC）是最常见且持续存在的类型之一，主要有两种组织学形式，即浅表型和结节型。典型的治疗方法包括手术；然而，手术可能会留下疤痕，这是不理想的，尤其是在面部病变中。我们报告了7例患有一个或多个基底细胞癌（包括结节型和浅表型）的个体患者使用5%咪喹莫特乳膏治疗的结果。13个病变中的11个在每日局部治疗10 - 18周后消退。治疗结束时，任何局部皮肤反应均得到缓解。
