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用于治疗膝关节血友病性关节病的截骨术的疗效

Outcome of osteotomies for the treatment of haemophilic arthropathy of the knee.

作者信息

Trieb K, Panotopoulos J, Hartl H, Brodner W, Pabinger I, Wanivenhaus A

机构信息

Department of Orthopaedics, University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

出版信息

Langenbecks Arch Surg. 2004 Jun;389(3):209-12. doi: 10.1007/s00423-003-0432-0. Epub 2003 Nov 14.

Abstract

BACKGROUND AND AIMS

The knee is one of the most commonly affected joints in haemophilic arthropathy leading to stiffness and disability. It is the aim of this study to investigate the outcome of corrective osteotomies around the knee.

PATIENTS AND METHODS

We report on the long-term results of ten osteotomies around the knee for severe haemophilic arthropathy and axial deviation at an average of 7.25+/-1.8 years postoperatively. Seven high tibial (preoperatively 7.2+/-2 degrees varus) and three supracondylar osteotomies (preoperatively 7+/-3 degrees valgus) were performed on seven patients (three of them bilateral).

RESULTS

The clinical score of the Advisory Board of the World Federation of Haemophilia (average 7.4 points preoperatively) remained unchanged in two patients, improved in three patients and deteriorated in five patients. The radiological Pettersson score (average 8.2 points preoperatively) showed a worsening of 2.5 points over the time. Patients reported a subjective improvement for seven osteotomies, with sports activity in three patients, although the range of motion did not change significantly. Total knee arthroplasty was considered to be a failure, i.e. endpoint of follow-up. Six knees were replaced in four patients by total arthroplasty after a mean of 6.6 years.

CONCLUSION

Although survival of osteotomies around the knee in haemophilic arthropathy is lower than in non-haemophilic patients, we think that it is a choice of treatment, which, at least, postpones the indication for total knee arthroplasty in this young patient group.

摘要

背景与目的

膝关节是血友病性关节病中最常受累的关节之一,可导致僵硬和残疾。本研究旨在探讨膝关节周围截骨矫正术的疗效。

患者与方法

我们报告了7例患者(其中3例为双侧)接受的膝关节周围截骨术治疗重度血友病性关节病及轴向畸形的长期结果,术后平均随访7.25±1.8年。共进行了7例高位胫骨截骨术(术前内翻7.2±2度)和3例髁上截骨术(术前外翻7±3度)。

结果

世界血友病联盟咨询委员会的临床评分(术前平均7.4分),2例患者保持不变,3例改善,5例恶化。放射学Pettersson评分(术前平均8.2分)随时间恶化2.5分。7例截骨术患者主观感觉有改善,3例患者恢复了体育活动,尽管活动范围无明显变化。全膝关节置换术被认为是失败的,即随访终点。平均6.6年后,4例患者的6个膝关节接受了全关节置换术。

结论

尽管血友病性关节病膝关节周围截骨术的生存率低于非血友病患者,但我们认为这是一种治疗选择,至少可以推迟该年轻患者群体全膝关节置换术的指征。

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