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血友病的骨科手术

Orthopaedic procedures in haemophilia.

作者信息

Rizzo Anna Rosa, Zago Manuel, Carulli Christian, Innocenti Massimo

机构信息

Orthopaedic Clinic, Department of Medicine and Translational Medicine, University of Florence, Italy.

出版信息

Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):197-199. doi: 10.11138/ccmbm/2017.14.1.197. Epub 2017 Oct 25.

Abstract

Haemophilia may nowadays be considered an "ortho paedic" disease given due to the involvement of musculoskeletal system in almost all haemophilic subjects. The modern haematological prophylaxis has dramatically improved the quality of life reducing bleedings and life-threatening complications; however, joint bleedings, progressive and irreversible arthropathy and osteoporosis are still now common challenging issues to be faced. One of the tissues involved by Haemophilia is the bone, particularly in the periarticular zone: poor bone quality and decrease of bone stock are typical patterns, and the worse is the arthropathy, the greater the bone loss. The orthopaedic management of such condition is now mandatory and characterized by several surgical techniques. The purpose of this work is to provide an overview of these options derived from our experience in managing haemophilic patients.

摘要

鉴于几乎所有血友病患者的肌肉骨骼系统都会受累,如今血友病可被视为一种“骨科”疾病。现代血液学预防措施已显著改善了生活质量,减少了出血和危及生命的并发症;然而,关节出血、进行性和不可逆的关节病以及骨质疏松症仍是目前常见的棘手问题。血友病累及的组织之一是骨骼,尤其是在关节周围区域:骨质不佳和骨量减少是典型表现,关节病越严重,骨质流失就越严重。现在,对这种病症进行骨科治疗是必要的,且有多种手术技术可供选择。本文的目的是根据我们治疗血友病患者的经验,对这些选择进行概述。

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Orthopaedic procedures in haemophilia.血友病的骨科手术
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本文引用的文献

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Hip Arthropathy in Haemophilia.血友病性髋关节病
J Clin Med. 2017 Apr 8;6(4):44. doi: 10.3390/jcm6040044.
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Tissue engineering applications in the management of bone loss.组织工程在骨质流失管理中的应用。
Clin Cases Miner Bone Metab. 2013 Jan;10(1):22-5. doi: 10.11138/ccmbm/2013.10.1.022.
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Aspects of current management: orthopaedic surgery in haemophilia.当前管理方面:血友病的矫形外科。
Haemophilia. 2012 Jan;18(1):8-16. doi: 10.1111/j.1365-2516.2011.02544.x. Epub 2011 Apr 27.

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