Sahler Olle Jane Z, Hunter Bryan C, Liesveld Jane L
University of Rochester Medical Center, USA.
Altern Ther Health Med. 2003 Nov-Dec;9(6):70-4.
Bone marrow/stem cell transplantation is becoming an increasingly common treatment for a variety of hematologic disorders. The treatment process is not benign. Both physiologic and psychological regimen-related side effects are common, painful, and even life threatening. Music therapy is the prescribed use of music to aid in the prevention or amelioration of physical, psychological, or cognitive problems. Relaxation imagery, as used in this study, consisted of simple visualization and direct imagery-based suggestions. The mechanism of action of the intervention is hypothesized to be reduction of the stress response through neuroendocrine pathways.
To determine the feasibility of providing a combined music therapy and relaxation imagery intervention to patients on a bone marrow transplant (BMT) unit and to examine the effects on the frequency and intensity of pain and nausea, the two most common side effects associated with transplantation.
Case controlled study.
University hospital-based bone marrow transplant unit serving patients of all ages.
Transplant recipients aged 4 years or older.
45-minute music-assisted relaxation and relaxation imagery sessions provided twice a week by a trained music therapist from date of enrollment into the study to discharge.
Pre/post music/relaxation imagery intervention measures of pain and nausea using a visual analog scale; determination of time-to-engraftment.
骨髓/干细胞移植正日益成为治疗各种血液系统疾病的常用方法。治疗过程并非无害。与治疗方案相关的生理和心理副作用都很常见,令人痛苦,甚至危及生命。音乐疗法是指有针对性地运用音乐来帮助预防或缓解身体、心理或认知问题。本研究中使用的放松想象法,包括简单的视觉化和基于直接想象的建议。据推测,该干预措施的作用机制是通过神经内分泌途径减轻应激反应。
确定在骨髓移植(BMT)病房为患者提供音乐疗法与放松想象相结合的干预措施的可行性,并研究其对疼痛和恶心这两种与移植相关的最常见副作用的发生频率和严重程度的影响。
病例对照研究。
一家为各年龄段患者服务的大学附属医院的骨髓移植病房。
4岁及以上的移植受者。
从入组研究之日起至出院,由一名经过培训的音乐治疗师每周两次提供45分钟的音乐辅助放松和放松想象治疗。
使用视觉模拟量表对音乐/放松想象干预前后的疼痛和恶心情况进行测量;确定植入时间。