Khuda-Bukhsh Anisur Rahman
Department of Zoology, University of Kalyani, Kalyani, West Bengal, India.
Mol Cell Biochem. 2003 Nov;253(1-2):339-45. doi: 10.1023/a:1026048907739.
The homeopathic mode of treatment often encourages use of drugs at such ultra-low doses and high dilutions that even the physical existence of a single molecule of the original drug substance becomes theoretically impossible. But homeopathy has sustained for over two hundred years despite periodical challenges thrown by scientists and non-believers regarding its scientificity. There has been a spurt of research activities on homeopathy in recent years, at clinical, physical, chemical, biological and medical levels with acceptable scientific norms and approach. While clinical effects of some homeopathic drugs could be convincingly shown, one of the greatest objections to this science lies in its inability to explain the mechanism of action of the microdoses based on scientific experimentations and proofs. Though many aspects of the mechanism of action still remain unclear, serious efforts have now been made to understand the molecular mechanism(s) of biological responses to the potentized form of homeopathic drugs. In this communication, an overview of some interesting scientific works on homeopathy has been presented with due emphasis on the state of information presently available on several aspects of the molecular mechanism of action of the potentized homeopathic drugs.
顺势疗法的治疗方式常常鼓励使用超低剂量和高稀释度的药物，以至于从理论上讲，原始药物物质的单个分子都不可能实际存在。尽管科学家和不信者不时对顺势疗法的科学性提出质疑，但顺势疗法已经持续了两百多年。近年来，在临床、物理、化学、生物和医学层面，人们以可接受的科学规范和方法，对顺势疗法展开了一系列研究活动。虽然一些顺势疗法药物的临床效果能够得到令人信服的证明，但这门科学最大的争议之一在于，它无法基于科学实验和证据来解释微剂量药物的作用机制。尽管作用机制的许多方面仍不明确，但目前人们已做出认真努力，去理解对顺势疗法药物进行增效处理后生物反应的分子机制。在本交流中，我们对一些关于顺势疗法的有趣科学研究进行了概述，并适当强调了目前在增效顺势疗法药物作用机制的几个方面所掌握的信息状况。
