Trisi Paolo, Marcato Carlo, Todisco Marzio
Biomaterials Clinical Research Association, Pescara, Italy.
Int J Periodontics Restorative Dent. 2003 Oct;23(5):427-37.
The goal of this study was to histologically document the effect of two different implant surfaces on the percentage of bone-to-implant apposition achieved with implants placed in human sinus grafts. The influences of implant site and post-grafting delay time were also examined. Nine healthy volunteers were scheduled to undergo posterior maxillary sinus floor augmentation in preparation for delayed implant placement. In addition to the conventional dental implants selected for each case, titanium alloy experimental implants, 2.5 mm in diameter and 8 mm in length, were custom manufactured. Each microimplant was prepared longitudinally with two different surface topographies: machined on one side and MTX microtextured on the other side. A notch prepared across the superior aspect of the implants facilitated placement and provided a reference line between the two surfaces. Patients were divided into two groups that received the experimental microimplants at the time of conventional implant placement: Group A (six patients) received the experimental microimplants in the regenerated lateral wall of the sinus graft 11 months after graft placement, and group B (three patients) received them in the alveolar crest 6 months after graft placement. After 6 months of submerged healing, all experimental and conventional implants appeared to be clinically osseointegrated. Histologic analysis revealed that the mean bone-to-implant apposition was significantly greater with MTX (72.31% +/- 17.76%) compared to machined surfaces (38.01% +/- 19.32%), regardless of bone quality. The healing time between graft and implant placement and implant location did not statistically impact the percentage of bone-to-implant apposition.
本研究的目的是通过组织学记录两种不同种植体表面对植入人上颌窦移植骨中的种植体实现的骨结合百分比的影响。还研究了种植部位和移植后延迟时间的影响。九名健康志愿者计划接受上颌后牙区窦底增高术，为延迟种植做准备。除了为每个病例选择的传统牙科种植体外，还定制制造了直径2.5毫米、长度8毫米的钛合金实验性种植体。每个微型种植体在纵向上制备有两种不同的表面形貌：一侧为机械加工表面，另一侧为MTX微纹理表面。在种植体上方制备的切口便于植入，并在两个表面之间提供了一条参考线。患者被分为两组，在常规种植体植入时接受实验性微型种植体：A组（六名患者）在移植后11个月在窦移植骨再生的侧壁接受实验性微型种植体，B组（三名患者）在移植后6个月在牙槽嵴接受实验性微型种植体。经过6个月的埋植愈合，所有实验性和传统种植体在临床上似乎都实现了骨整合。组织学分析显示，无论骨质量如何，与机械加工表面（38.01%±19.32%）相比，MTX表面的平均骨结合率（72.31%±17.76%）显著更高。移植与种植体植入之间的愈合时间以及种植体位置对骨结合百分比没有统计学影响。
