Al Deeb Modhi, Aldosari Abdullah AlFarraj, Anil Sukumaran
Department of Prosthetic Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar.
J Funct Biomater. 2023 Jul 6;14(7):355. doi: 10.3390/jfb14070355.
This study aimed to investigate the impact of the Tantalum Trabecular Metal dental implant design on implant stability and the process of osseointegration following its placement in the rabbit femoral condyle. The subjects for the experiment consisted of 10 New Zealand white rabbits. Twenty implants, comprising 10 Trabecular Metal (TM) and 10 Traditional Screw Vent (TSV) implants, were placed into the femoral condyles of these rabbits. The implant type was alternated based on a random sequence. Following a healing period of 8 weeks, the implants were retrieved for further analysis using micro-computed tomography (micro-CT), histological studies, and histomorphometry evaluations. The Bone-to-Implant Contact (BIC) ratio and the Bone Volume (BV) percentage in the region of interest were subsequently assessed. The BIC and BV values between TM and TSV implants were compared using the Student -test. The TM implants exhibited significantly greater BIC and BV scores. In particular, the BIC percentage was recorded as 57.9 ± 6.5 for the TM implants, as opposed to 47.6 ± 8 for the TSV implants. Correspondingly, the BV percentage was 57 ± 7.3 for the TM implants and 46.4 ± 7.4 for the TSV implants. The bone volume percentage measured using micro-CT evaluation was 89.1 ± 8.7 for the TM implants and 79.1 ± 8.6 for the TSV implants. Given the observed results, it is plausible to suggest that the bone growth surrounding the tantalum mesh could have improved the integration of the bone and facilitated its ingrowth into the TM implant.
本研究旨在调查钽小梁金属牙种植体设计对种植体稳定性的影响，以及将其植入兔股骨髁后骨整合的过程。实验对象为10只新西兰白兔。将20枚种植体（包括10枚小梁金属（TM）种植体和10枚传统螺旋通风（TSV）种植体）植入这些兔子的股骨髁。种植体类型根据随机顺序交替使用。经过8周的愈合期后，取出种植体，使用微型计算机断层扫描（micro-CT）、组织学研究和组织形态计量学评估进行进一步分析。随后评估感兴趣区域的骨与种植体接触（BIC）比率和骨体积（BV）百分比。使用学生t检验比较TM和TSV种植体之间的BIC和BV值。TM种植体表现出明显更高的BIC和BV评分。特别是，TM种植体的BIC百分比记录为57.9±6.5，而TSV种植体为47.6±8。相应地，TM种植体的BV百分比为57±7.3，TSV种植体为46.4±7.4。使用micro-CT评估测量的骨体积百分比，TM种植体为89.1±8.7，TSV种植体为79.1±8.6。鉴于观察结果，有理由认为钽网周围的骨生长可能改善了骨的整合，并促进了骨向内生长到TM种植体中。
