Goulet Olivier, Révillon Yann
Combined Programme of Intestinal Transplantation Hôspital Necker-Enfants Malades, Paris, France.
Indian J Pediatr. 2003 Sep;70(9):737-42. doi: 10.1007/BF02724317.
Advances in immunosuppressive treatment as well as better monitoring and control of acute rejection have brought intestinal transplantation (ITx) into the realm of standard treatment for permanent intestinal failure. The results from the intestinal Transplant International Registry (www.intestinaltransplant.org) indicate that ITx is currently an acceptable clinical modality for selected patients with permanent intestinal failure. The goal of this short review is to deal with indications, clinical results and complications of ITx. Although it has been used in humans for the past two decades, very few data are available regarding graft function and its monitoring.
免疫抑制治疗的进展以及对急性排斥反应更好的监测和控制,已将肠道移植(ITx)带入了永久性肠衰竭标准治疗的领域。国际肠道移植登记处(www.intestinaltransplant.org)的结果表明,目前ITx对于选定的永久性肠衰竭患者是一种可接受的临床治疗方式。这篇简短综述的目的是探讨ITx 的适应证、临床结果和并发症。尽管在过去二十年中它已应用于人类,但关于移植物功能及其监测的可用数据非常少。