Schweizer G, Hilbe M, Braun U
Department of Veterinary Internal Medicine, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland.
Vet Rec. 2003 Oct 25;153(17):525-8. doi: 10.1136/vr.153.17.525.
This paper describes the clinical, haematological, immunohistochemical and pathological findings in 10 female cattle with cutaneous lymphoma. The most striking clinical finding was multifocal intracutaneous nodules, which were firm, hairless and sometimes covered with haemorrhagic crusts. All the animals had multiple lymphadenopathy. Eight of the animals had leucocytosis and two also had lymphocytosis. In seven animals, a definitive diagnosis of lymphosarcoma was made on the basis of biopsies of intracutaneous nodules or fine needle aspirates of superficial lymph nodes. In some of the cattle the kidneys, heart, spleen and lungs were affected.
本文描述了10头患有皮肤淋巴瘤的雌性牛的临床、血液学、免疫组织化学和病理学发现。最显著的临床发现是多灶性皮内结节,质地坚硬、无毛,有时覆盖有出血性痂皮。所有动物均有多处淋巴结病。8只动物有白细胞增多症,2只也有淋巴细胞增多症。7只动物根据皮内结节活检或浅表淋巴结细针穿刺抽吸物做出了淋巴肉瘤的明确诊断。部分牛的肾脏、心脏、脾脏和肺也受到影响。