Rook Kathryn A
Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA.
Vet Clin North Am Small Anim Pract. 2019 Jan;49(1):67-81. doi: 10.1016/j.cvsm.2018.08.007. Epub 2018 Sep 24.
Cutaneous lymphomas are divided into categories based on histologic evaluation of the skin and location of neoplastic lymphocytes. Epitheliotropic cutaneous lymphoma, also known as cutaneous T-cell lymphoma, is diagnosed when neoplastic lymphocytes show tropism for the epidermis and these cells infiltrate the epidermis and adnexae. In diagnosis of nonepitheliotropic cutaneous lymphoma, neoplastic lymphocytes are found mostly in the dermis and/or subcutis. Neoplastic cells are of either B-cell or T-cell origin. This article focuses on epitheliotropic cutaneous lymphomas and cutaneous lymphocytosis, which is considered a form of indolent lymphoma, in dogs and cats.
皮肤淋巴瘤根据皮肤的组织学评估和肿瘤性淋巴细胞的位置进行分类。亲表皮性皮肤淋巴瘤,也称为皮肤T细胞淋巴瘤,当肿瘤性淋巴细胞表现出对表皮的嗜性且这些细胞浸润表皮和附属器时可作出诊断。在非亲表皮性皮肤淋巴瘤的诊断中,肿瘤性淋巴细胞大多见于真皮和/或皮下组织。肿瘤细胞起源于B细胞或T细胞。本文重点关注犬猫的亲表皮性皮肤淋巴瘤和皮肤淋巴细胞增多症,后者被认为是一种惰性淋巴瘤。