Conceição Fabrício Rochedo, Paolicchi Fernando, Cobo Ana Lia, Gil-Turnes Carlos
Centro de Biotecnologia e Faculdade de Veterinária, Universidade Federal de Pelotas, CP 354, 96010-900, Pelotas, Brasil.
Can J Vet Res. 2003 Oct;67(4):315-8.
Cross-reactivity indices (CRIs) of 28 isolates of Moraxella bovis recovered from outbreaks of infectious bovine keratoconjunctivitis in Argentina (A, 11 isolates), Brazil (B, 7), and Uruguay (U, 10) between 1983 and 2000 were estimated. Hyperimmune sera were produced in rabbits and antibody titres determined with each isolate. Isolates showing CRIs3 70 were placed in the same group. Group I had 13 isolates (A, 1; B, 6; U, 6); group II had 6 isolates (A, 4; U, 2); groups III, IV, and V had 2 isolates each, recovered in Argentina; group VI had 2 isolates, from Uruguay; and group VII had 1 isolate, from Brazil. The CRIs3 70 between vaccine strains and isolates recovered before and after 1990 were 58% and 42%, 50% and 50%, and 33% and 67% with vaccine strains 2419, 2358, and 2439, respectively. Isolate 273, from Uruguay, showed CRIs > 70 with 78% of the isolates and is recommended as the vaccine strain.
对1983年至2000年间从阿根廷（A组，11株分离株）、巴西（B组，7株）和乌拉圭（U组，10株）的传染性牛角膜结膜炎疫情中分离出的28株牛莫拉菌的交叉反应指数（CRIs）进行了评估。用兔制备了超免疫血清，并测定了每种分离株的抗体滴度。交叉反应指数≥70的分离株归为同一组。第一组有13株分离株（A组1株、B组6株、U组6株）；第二组有6株分离株（A组4株、U组2株）；第三、四、五组每组有2株分离株，均从阿根廷分离得到；第六组有2株分离株，来自乌拉圭；第七组有1株分离株，来自巴西。疫苗株2419、2358和2439与1990年之前和之后分离得到的分离株之间交叉反应指数≥70的情况分别为58%和42%、50%和50%、33%和67%。来自乌拉圭的分离株273与78%的分离株交叉反应指数>70，推荐作为疫苗株。
