Profili S, Feo C F, Meloni G B, Strusi G, Cossu M L, Canalis G C
Dept. of Radiology, University of Sassari, Sassari, Italy.
Scand J Gastroenterol. 2003 Oct;38(10):1099-102. doi: 10.1080/00365520310005532.
The aim of this case report was to evaluate the usefulness of combined biliary and duodenal stenting in the palliation of pancreatic cancer. We report a series of 4 consecutive patients (2 men and 2 women, mean age 58.5 years, range 38-77 years) who underwent combined biliary and duodenal stenting in our department between March 2000 and April 2001. All patients had cancer of the head of the pancreas causing stricture of the common bile duct and second portion of the duodenum. Biliary and duodenal stents were successfully positioned, with relief of symptoms in all cases. No early complications were observed, except for a transient increase in serum lipase and amylase in one case. Mean follow-up was 7.5 months (range 5-14 months). One patient presenting recurrence of vomiting after 4 months because of tumour overgrowth at the distal edge of the prosthesis was successfully treated by insertion of a partially overlapping second coaxial stent. Combined biliary and duodenal stenting for the palliation of pancreatic cancer was performed safely and successfully. Stents allowed effective re-canalization of the biliary tract and duodenum, relieving both jaundice and vomiting. This procedure should be considered as an alternative to palliative surgery, especially in critically ill patients.
本病例报告的目的是评估联合胆管和十二指肠支架置入术在胰腺癌姑息治疗中的有效性。我们报告了2000年3月至2001年4月期间在我科接受联合胆管和十二指肠支架置入术的4例连续患者(2例男性,2例女性,平均年龄58.5岁,年龄范围38 - 77岁)。所有患者均患有胰头癌,导致胆总管和十二指肠第二部狭窄。胆管和十二指肠支架均成功置入,所有病例症状均缓解。除1例患者血清脂肪酶和淀粉酶短暂升高外,未观察到早期并发症。平均随访7.5个月(范围5 - 14个月)。1例患者在4个月后因假体远端边缘肿瘤过度生长出现呕吐复发,通过插入部分重叠的第二个同轴支架成功治疗。联合胆管和十二指肠支架置入术用于胰腺癌的姑息治疗安全且成功。支架可有效使胆道和十二指肠再通,缓解黄疸和呕吐症状。该手术应被视为姑息性手术的替代方案,尤其是对于重症患者。