Olsen Eydfinnur, Kiil Jørgen, Petersen Jørgen Bruun
Viborg Sygehus, Organkirurgisk Afdeling og Billeddiagnostisk Afdeling.
Ugeskr Laeger. 2005 Sep 26;167(39):3678-81.
Self-expanding metal stents (SEMS) have emerged as a simple therapeutic option for the palliation of patients with non-resectable malignant gastric outlet obstruction. We present our results from a three-year period.
Twenty-nine patients with obstruction from tumors in the pancreas (15), bile ducts (3), stomach (9) or transverse colon (2) underwent palliative stenting with a 9-cm-long, 22 mm Wallstent under general anaesthesia. Insertion of the SEMS was done under endoscopic and fluoroscopic control. Biliary stents were implanted prior to or simultaneously with the duodenal stent in eight patients. Seven were covered 6-cm-long, 10 mm Wallstents. Two patients had biliary stents implanted 12 and 262 days, respectively, after the duodenal stent by "rendezvous" technique.
The stent deployment was successful in all patients. There were no procedure-related complications, but one patient died of cardiac arrest 12 hours after the operation. Obstruction was relieved in all patients, and an exclusively oral diet was possible for 23 of them. Seven patients with rapid progression of the disease stayed in hospital and died 0-16 days after the procedure. The median length of stay in hospital after the procedure was 2 days (1-32 days), after which the patients stayed at home for 40 days (2-270 days). The overall median survival time was 47 days (median, 0-274 days). There were no late complications (stent migration or perforation), but two patients needed an overlapping stent due to tumor overgrowth.
Duodenal stents effectively resolve the obstructive symptoms of gastric outlet obstruction. There are few procedure-related complications, and the vast majority of patients can leave hospital and spend the short time left to them at home.
自膨式金属支架(SEMS)已成为治疗不可切除性恶性胃出口梗阻患者的一种简单治疗选择。我们展示了三年期间的研究结果。
29例因胰腺(15例)、胆管(3例)、胃(9例)或横结肠(2例)肿瘤导致梗阻的患者在全身麻醉下接受了9厘米长、22毫米的Wallstent姑息性支架置入术。SEMS的置入在内镜和荧光镜控制下进行。8例患者在十二指肠支架置入之前或同时植入了胆管支架。7例患者植入了6厘米长、覆盖型10毫米的Wallstent。2例患者分别在十二指肠支架置入后12天和262天通过“会师”技术植入了胆管支架。
所有患者支架置入均成功。无手术相关并发症,但1例患者术后12小时死于心脏骤停。所有患者梗阻均得到缓解,其中23例患者能够完全经口进食。7例疾病进展迅速的患者住院并在术后0至16天死亡。术后住院时间中位数为2天(1至32天),之后患者在家中停留40天(2至270天)。总体生存时间中位数为47天(中位数,0至274天)。无晚期并发症(支架移位或穿孔),但2例患者因肿瘤过度生长需要植入重叠支架。
十二指肠支架可有效缓解胃出口梗阻的梗阻症状。手术相关并发症较少,绝大多数患者能够出院并在家中度过剩余的短暂时间。