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视觉模拟量表评分及变化分数的解读:两项术后疼痛临床试验的再分析

Interpretation of visual analog scale ratings and change scores: a reanalysis of two clinical trials of postoperative pain.

作者信息

Jensen Mark P, Chen Connie, Brugger Andrew M

机构信息

Department of Rehabilitation Medicine, School of Medicine, and Multidisciplinary Pain Center, University of Washington, Seattle, WA 98195-6490, USA.

出版信息

J Pain. 2003 Sep;4(7):407-14. doi: 10.1016/s1526-5900(03)00716-8.

Abstract

The visual analog scale (VAS) is one of the most commonly used measures of pain intensity in pain research. However, there remain important unanswered questions concerning interpretation of specific VAS ratings and change scores. To address these questions, we performed a reanalysis of data from 2 randomized controlled trials of postoperative pain (N = 123 and N = 125) to determine the meaning of VAS pain intensity ratings and change scores. The findings suggested that 100-mm VAS ratings of 0 to 4 mm can be considered no pain; 5 to 44 mm, mild pain; 45 to 74 mm, moderate pain; and 75 to 100 mm, severe pain. As predicted, in assessment of the amount of change corresponding to differing levels of pain relief, percentage change in a patient's VAS score was less biased by pretreatment pain than was absolute change score. The findings also suggested that a 33% decrease in pain represents a reasonable standard for determining that a change in pain is meaningful from the patient's perspective.

摘要

视觉模拟评分法(VAS)是疼痛研究中最常用的疼痛强度测量方法之一。然而,关于特定VAS评分及变化分数的解读仍存在重要的未解决问题。为解决这些问题,我们对两项术后疼痛随机对照试验(N = 123和N = 125)的数据进行了重新分析,以确定VAS疼痛强度评分及变化分数的意义。研究结果表明,100毫米VAS评分中0至4毫米可视为无痛;5至44毫米为轻度疼痛;45至74毫米为中度疼痛;75至100毫米为重度疼痛。正如预期的那样,在评估与不同程度疼痛缓解相对应的变化量时,患者VAS评分的百分比变化比绝对变化分数受治疗前疼痛的影响更小。研究结果还表明,疼痛减轻33%代表了从患者角度确定疼痛变化有意义的合理标准。

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