Aicardi S, Durin L, Dompmartin A, Dreyfus M
Clinique de gynécologie-obstétrique, CHU de Caen, avenue Georges-Clemenceau, 14033 Caen, France.
Gynecol Obstet Fertil. 2003 Nov;31(11):940-2. doi: 10.1016/j.gyobfe.2003.09.004.
Pemphigoid gestationis is a gestational skin disease usually appearing between the 28th and the 32nd week of amenorrhea. It is a rare vesiculobullous skin disease and the eruption is located around the umbilicus. The diagnosis is made with clinical symptoms but mainly on histologic examination (after skin biopsy) and direct immunofluorescence. One of the main complications is the rate of recurrence. The main treatment is based on topical corticosteroids. The effects of the pemphigoid gestationis are maternal (preterm labor), fetal (intrauterine growth retardation) and neonatal (bullous disease). We report a case of pemphigoid gestationis associated to a gestational hypertensive disorder and we try to rely on both entities.
妊娠类天疱疮是一种妊娠期皮肤病,通常在闭经第28至32周出现。它是一种罕见的水疱大疱性皮肤病,皮疹位于脐周。诊断依据临床症状,但主要基于组织学检查(皮肤活检后)和直接免疫荧光检查。主要并发症之一是复发率。主要治疗方法是外用糖皮质激素。妊娠类天疱疮的影响涉及母体(早产)、胎儿(宫内生长受限)和新生儿(大疱性疾病)。我们报告一例妊娠类天疱疮合并妊娠期高血压疾病的病例,并尝试对这两种情况进行分析。